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Name	Group	Epoch	Country	Sex	Year from	Year to	Haplogroup	Sequence source	Avg. coverage	Reference	Download	Pathologies
I0644	CANE	Copper Age	Israel	F	-4500	-3900	H4	<NA>	0.87	Harney et al. 2018 Data	FASTA Metadata
I1154	CANE	Copper Age	Israel	F	-4500	-3900	T2g1a	<NA>	0.05	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
I1155	CANE	Copper Age	Israel	M	-4500	-3900	K1a	<NA>	0.09	Harney et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
I1160	CANE	Copper Age	Israel	M	-4500	-3900	N1a1b	<NA>	1.31	Harney et al. 2018 Data	FASTA Metadata	15043A (MT-CYB): MDD-associated (Reported)
I1164	CANE	Copper Age	Israel	F	-4500	-3900	J2a2d	<NA>	0.36	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15257A (MT-CYB): LHON (Conflicting reports) 195C (MT-CR): BD-associated / melanoma pts (Reported) 295T (MT-CR): Low VO2max response (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported)
I1165	CANE	Copper Age	Israel	M	-4500	-3900	HV1a’b’c’	<NA>	0.95	Harney et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
I1166	CANE	Copper Age	Israel	M	-4500	-3900	H	<NA>	0.98	Harney et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3316A (MT-ND1): Diabetes / LHON / PEO (Unclear)
I1168	CANE	Copper Age	Israel	F	-4500	-3900	T2+150	<NA>	1.06	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
I1170	CANE	Copper Age	Israel	M	-4500	-3900	T1a2	<NA>	0.67	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
I1171	CANE	Copper Age	Israel	M	-4500	-3900	K	<NA>	0.26	Harney et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
I1172	CANE	Copper Age	Israel	M	-4500	-3900	K1a	<NA>	0.12	Harney et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
I1178	CANE	Copper Age	Israel	M	-4500	-3900	16	<NA>	2.56	Harney et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 15924G (MT-TT): LIMM (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
I1179	CANE	Copper Age	Israel	F	-4500	-3900	T2	<NA>	0.51	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
I1181	CANE	Copper Age	Israel	F	-4500	-3900	T2	<NA>	0.09	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
I1182	CANE	Copper Age	Israel	F	-4500	-3900	T1a+152	<NA>	0.63	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
I1183	CANE	Copper Age	Israel	F	-4500	-3900	R0a	<NA>	0.45	Harney et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3275A (MT-TL1): LHON (Reported)
I1184	CANE	Copper Age	Israel	F	-4500	-3900	T1a+152	<NA>	0.41	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
I1169	CANE	Copper Age	Israel	F	-4500	-3900	J2a2d	<NA>	8.29	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15257A (MT-CYB): LHON (Conflicting reports) 195C (MT-CR): BD-associated / melanoma pts (Reported) 295T (MT-CR): Low VO2max response (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported)
I1177	CANE	Copper Age	Israel	F	-4500	-3900	N1b1	<NA>	0.09	Harney et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 8836G (MT-ATP6): LHON (Reported)
I1187	CANE	Copper Age	Israel	M	-4500	-3900	U6d	<NA>	0.12	Harney et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14696G (MT-TE): Progressive Encephalopathy (Reported) 15784C (MT-CYB): POAG - potential for association (Reported) 16390A (MT-CR): POAG - potential for association (Reported) 3316A (MT-ND1): Diabetes / LHON / PEO (Unclear) 8836G (MT-ATP6): LHON (Reported)
I1152	CANE	Copper Age	Israel	F	-4500	-3900	J2a2d	<NA>	1.14	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15257A (MT-CYB): LHON (Conflicting reports) 195C (MT-CR): BD-associated / melanoma pts (Reported) 295T (MT-CR): Low VO2max response (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported)
I1180	CANE	Copper Age	Israel	M	-4500	-3900	T	<NA>	0.09	Harney et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)