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Name	Group	Epoch	Country	Sex	Year from	Year to	Haplogroup	Sequence source	Avg. coverage	Reference	Download	Pathologies
HUGO_167	BBC	Bronze Age	Germany	M	-2270	-2039	U5b2b3a	reconstructed	195.80	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12634G (MT-ND5): Thyroid Cancer Cell Line (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 2755G (MT-RNR2): Possibly LVNC-associated (Reported) 16270T (MT-CR): Melanoma patients (Reported)
HUGO_168	BBC	Bronze Age	Germany	F	-2289	-2141	H1	reconstructed	620.10	Knipper et al. 2017 Data	FASTA Metadata	3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
POST_3	EBAGe	Bronze Age	Germany	U	-2019	-1890	None	<NA>	3.50	Knipper et al. 2017 Data	Metadata
POST_16	EBAGe	Bronze Age	Germany	F	-2029	-1911	T2f8a	reconstructed	303.40	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 3243G (MT-TL1): MELAS / Leigh Syndrome / DMDF / MIDD / SNHL / CPEO / MM / FSGS / ASD / Cardiac+multi-organ dysfunction (Cfrm) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
HUGO_169sk1	BBC	Bronze Age	Germany	M	-2562	-2345	U5a2b3	reconstructed	949.10	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
POST_21	EBAGe	Bronze Age	Germany	M	-2025	-1903	None	<NA>	3.60	Knipper et al. 2017 Data	Metadata
POST_32	EBAGe	Bronze Age	Germany	F	-2032	-1916	T2	reconstructed	1048.10	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
HUGO_169sk2	BBC	Bronze Age	Germany	F	-2461	-2211	U5a2b3	reconstructed	35.10	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
POST_38	EBAGe	Bronze Age	Germany	M	-2197	-2034	H1e	reconstructed	38.30	Knipper et al. 2017 Data	FASTA Metadata	16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
HUGO_170	BBC	Bronze Age	Germany	M	-2288	-2066	U4d3	reconstructed	475.40	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 14577C (MT-ND6): MIDM (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 499A (MT-CR): Endometriosis (Reported)
HUGO_171	BBC	Bronze Age	Germany	F	-2387	-2146	U5a1a1	reconstructed	424.90	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15924G (MT-TT): LIMM (Reported) 16270T (MT-CR): Melanoma patients (Reported)
HUGO_180sk	BBC	Bronze Age	Germany	M	-2461	-2210	U5b2b4	reconstructed	1693.00	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12634G (MT-ND5): Thyroid Cancer Cell Line (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
HUGO_180sk2	BBC	Bronze Age	Germany	M	-2463	-2235	U5b2b4	reconstructed	879.30	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12634G (MT-ND5): Thyroid Cancer Cell Line (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
HUGO_190	BBC	Bronze Age	Germany	F	-2268	-2046	J1c3g	reconstructed	130.90	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 185A (MT-CR): Low VO2max response (Reported) 295T (MT-CR): Low VO2max response (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 228A (MT-CR): Low VO2max response (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported)
POST_1	EBAGe	Bronze Age	Germany	F	-2024	-1882	H2a1a	reconstructed	280.30	Knipper et al. 2017 Data	FASTA Metadata
POST_85	EBAGe	Bronze Age	Germany	U	-2120	-1921	X2b+226	reconstructed	298.90	Knipper et al. 2017 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 8393T (MT-ATP8): Reversible brain pseudoatrophy (Reported)
POST_2	EBAGe	Bronze Age	Germany	U	-2126	-1948	None	<NA>	1.30	Knipper et al. 2017 Data	Metadata
POST_6	EBAGe	Bronze Age	Germany	M	-2009	-1883	U5a1a1+16362	reconstructed	233.80	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15924G (MT-TT): LIMM (Reported) 16270T (MT-CR): Melanoma patients (Reported)
POST_12	EBAGe	Bronze Age	Germany	U	-2190	-2028	J1c3g	reconstructed	14.60	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 185A (MT-CR): Low VO2max response (Reported) 295T (MT-CR): Low VO2max response (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4435G (MT-TM): LHON modulator / hypertension / autism spectrum / intellectual disability (Reported) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported)
POST_137	EBAGe	Bronze Age	Germany	M	-2029	-1912	T2c1d+152	reconstructed	46.90	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported) 6261A (MT-CO1): Prostate Cancer / LHON (Reported)
POST_24	EBAGe	Bronze Age	Germany	M	-2137	-1980	H1b1	reconstructed	1314.80	Knipper et al. 2017 Data	FASTA Metadata	16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 3796G (MT-ND1): Adult-Onset Dystonia (Reported)
POST_28	EBAGe	Bronze Age	Germany	M	-2027	-1906	K2a5	reconstructed	54.90	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
UNTA58-62_67	BBC	Bronze Age	Germany	M	-2455	-2204	K1a	reconstructed	1521.50	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_148	EBAGe	Bronze Age	Germany	U	-2470	-1776	None	<NA>	<NA>	Knipper et al. 2017 Data	Metadata
POST_35	EBAGe	Bronze Age	Germany	F	-2033	-1918	H41a	reconstructed	868.70	Knipper et al. 2017 Data	FASTA Metadata	5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
POST_44	EBAGe	Bronze Age	Germany	M	-2139	-1979	K1a3a	reconstructed	684.20	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
POST_47	EBAGe	Bronze Age	Germany	M	-2134	-1956	K2a5	reconstructed	26.80	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
UNTA85_113	BBC	Bronze Age	Germany	M	-2456	-2155	U5b2a3	reconstructed	33.70	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
UNTA85_1334	BBC	Bronze Age	Germany	M	-2453	-2152	H15a1	reconstructed	58.40	Knipper et al. 2017 Data	FASTA Metadata	6253C (MT-CO1): Prostate Cancer / enriched in POAG cohort (Reported)
UNTA85_1336	BBC	Bronze Age	Germany	F	-2465	-2300	H2a1	reconstructed	54.30	Knipper et al. 2017 Data	FASTA Metadata
POST_50	EBAGe	Bronze Age	Germany	M	-2196	-2029	T1a1	reconstructed	328.30	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
UNTA85_1412	EBAGe	Bronze Age	Germany	M	-2025	-1895	H	<NA>	134.50	Knipper et al. 2017 Data	Metadata
OBKR_9B	EBAGe	Bronze Age	Germany	F	-2032	-1903	U5a1i1	reconstructed	160.00	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
OBKR_47	EBAGe	Bronze Age	Germany	M	-2136	-1977	J2b1a	reconstructed	511.40	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12397G (MT-ND5): PD / early onset (Reported) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15257A (MT-CYB): LHON (Conflicting reports) 15812A (MT-CYB): LHON (Reported / Secondary) 295T (MT-CR): Low VO2max response (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported)
OBKR_50	EBAGe	Bronze Age	Germany	F	-2112	-1912	HV0	reconstructed	83.80	Knipper et al. 2017 Data	FASTA Metadata
POST_84	EBAGe	Bronze Age	Germany	F	-2126	-1928	X2b+226	reconstructed	189.50	Knipper et al. 2017 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 8393T (MT-ATP8): Reversible brain pseudoatrophy (Reported)
POST_99	EBAGe	Bronze Age	Germany	F	-2130	-1930	K1a4a1	<NA>	176.70	Knipper et al. 2017 Data	Metadata
OBKR_82	EBAGe	Bronze Age	Germany	F	-2023	-1894	X2b	reconstructed	184.40	Knipper et al. 2017 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 8393T (MT-ATP8): Reversible brain pseudoatrophy (Reported)
OBKR_85	EBAGe	Bronze Age	Germany	F	-2113	-1915	H27	reconstructed	520.20	Knipper et al. 2017 Data	FASTA Metadata	16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
POST_111	EBAGe	Bronze Age	Germany	F	-2122	-1941	U5b2b2	reconstructed	29.40	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12634G (MT-ND5): Thyroid Cancer Cell Line (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16270T (MT-CR): Melanoma patients (Reported)
WEHR_1414	EBAGe	Bronze Age	Germany	U	-2022	-1897	K1a1b1g	reconstructed	390.80	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15924G (MT-TT): LIMM (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
WEHR_1586	EBAGe	Bronze Age	Germany	F	-1951	-1779	V	reconstructed	57.80	Knipper et al. 2017 Data	FASTA Metadata
POST_131	EBAGe	Bronze Age	Germany	F	-2120	-1938	T2c1d+152	reconstructed	162.10	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported) 6261A (MT-CO1): Prostate Cancer / LHON (Reported)
POST_140	EBAGe	Bronze Age	Germany	M	-2114	-1926	H41a	reconstructed	21.00	Knipper et al. 2017 Data	FASTA Metadata	5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
UNTA58-62_68Sk1	BBC	Bronze Age	Germany	M	-2470	-1776	J1c	reconstructed	691.00	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_68Sk2	BBC	Bronze Age	Germany	F	-2470	-2310	K1a	reconstructed	641.40	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_146	EBAGe	Bronze Age	Germany	U	-2009	-1881	H1c	reconstructed	852.20	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_147	EBAGe	Bronze Age	Germany	F	-2031	-1900	H2a1	reconstructed	372.40	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_149	EBAGe	Bronze Age	Germany	U	-2023	-1892	K1a1b1g	reconstructed	767.10	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_150	EBAGe	Bronze Age	Germany	U	-2009	-1780	U5b1c2	reconstructed	1225.10	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_151	EBAGe	Bronze Age	Germany	U	-1946	-1886	U5b1c2	reconstructed	64.20	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_152	EBAGe	Bronze Age	Germany	U	-2007	-1779	U5b1c2	reconstructed	774.50	Knipper et al. 2017 Data	FASTA Metadata
UNTA58-62_153	EBAGe	Bronze Age	Germany	M	-1971	-1776	R1a1a	reconstructed	267.60	Knipper et al. 2017 Data	FASTA Metadata
UNTA85_110	BBC	Bronze Age	Germany	F	-2290	-2141	J1c1b1a	reconstructed	15.40	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 185A (MT-CR): Low VO2max response (Reported) 295T (MT-CR): Low VO2max response (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 228A (MT-CR): Low VO2max response (Reported) 3394C (MT-ND1): LHON / Diabetes / CPTdeficiency / high altitude adaptation (Reported / Population-dependent) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported)
UNTA85_1343	BBC	Bronze Age	Germany	M	-2397	-2149	J1c2	reconstructed	417.00	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 185A (MT-CR): Low VO2max response (Reported) 295T (MT-CR): Low VO2max response (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 228A (MT-CR): Low VO2max response (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported)
UNTA85_1163	EBAGe	Bronze Age	Germany	M	-2021	-1885	H23	reconstructed	192.30	Knipper et al. 2017 Data	FASTA Metadata	1555G (MT-RNR1): DEAF / autism spectrum intellectual disability / possibly antiatherosclerotic (Cfrm)
OBKR_2	EBAGe	Bronze Age	Germany	F	-2023	-1894	K1a4a1	reconstructed	855.00	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
OBKR_5	EBAGe	Bronze Age	Germany	U	-2113	-1917	V7	reconstructed	34.20	Knipper et al. 2017 Data	FASTA Metadata	15924G (MT-TT): LIMM (Reported) 7444A (MT-CO1): LHON / SNHL / DEAF (Reported)
OBKR_6	EBAGe	Bronze Age	Germany	F	-2029	-1903	V7	reconstructed	854.80	Knipper et al. 2017 Data	FASTA Metadata	15924G (MT-TT): LIMM (Reported) 7444A (MT-CO1): LHON / SNHL / DEAF (Reported)
OBKR_9A	EBAGe	Bronze Age	Germany	F	-2022	-1892	K1a2a	reconstructed	1004.40	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
OBKR_26	EBAGe	Bronze Age	Germany	F	-2033	-1907	HV	reconstructed	391.40	Knipper et al. 2017 Data	FASTA Metadata	16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
OBKR_66	EBAGe	Bronze Age	Germany	F	-2028	-1903	U4a	reconstructed	319.40	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 499A (MT-CR): Endometriosis (Reported)
OBKR_67	EBAGe	Bronze Age	Germany	M	-2023	-1894	K2a5	reconstructed	147.20	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
OBKR_73	EBAGe	Bronze Age	Germany	F	-2024	-1897	U5b2a1a1	reconstructed	3834.40	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16192T (MT-CR): Melanoma patients (Reported)
OBKR_76	EBAGe	Bronze Age	Germany	F	-2013	-1785	K1a	reconstructed	253.90	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
OBKR_79	EBAGe	Bronze Age	Germany	U	-2018	-1883	H1ba	reconstructed	107.40	Knipper et al. 2017 Data	FASTA Metadata	16270T (MT-CR): Melanoma patients (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
OBKR_80	EBAGe	Bronze Age	Germany	M	-2134	-1959	K1a3	reconstructed	627.20	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 9055A (MT-ATP6): PD protective factor (Reported)
OBKR_81	EBAGe	Bronze Age	Germany	F	-2024	-1896	X2b	reconstructed	715.20	Knipper et al. 2017 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 8393T (MT-ATP8): Reversible brain pseudoatrophy (Reported)
OBKR_84	EBAGe	Bronze Age	Germany	F	-2021	-1830	V7	reconstructed	663.10	Knipper et al. 2017 Data	FASTA Metadata	15924G (MT-TT): LIMM (Reported) 7444A (MT-CO1): LHON / SNHL / DEAF (Reported)
OBKR_86	EBAGe	Bronze Age	Germany	M	-2032	-1901	K1a3	reconstructed	210.60	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 9055A (MT-ATP6): PD protective factor (Reported)
OBKR_93	EBAGe	Bronze Age	Germany	F	-2111	-1907	K1a4a1	reconstructed	2029.00	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
OBKR_95	EBAGe	Bronze Age	Germany	F	-2027	-1901	V1a	reconstructed	461.40	Knipper et al. 2017 Data	FASTA Metadata	16390A (MT-CR): POAG - potential for association (Reported)
OBKR_96	EBAGe	Bronze Age	Germany	F	-2013	-1784	H1j2	reconstructed	113.10	Knipper et al. 2017 Data	FASTA Metadata	13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
OBKR_117	EBAGe	Bronze Age	Germany	M	-2019	-1883	U4a1b	reconstructed	1731.20	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 499A (MT-CR): Endometriosis (Reported) 745G (MT-RNR1): DEAF-associated (Reported)
WEHR_1192SkA	BBC	Bronze Age	Germany	M	-2331	-2150	K1a4a1	reconstructed	1611.30	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
WEHR_1192SkB	EBAGe	Bronze Age	Germany	F	-1918	-1772	U5b2a2b	reconstructed	3962.80	Knipper et al. 2017 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
WEHR_1193	EBAGe	Bronze Age	Germany	F	-1945	-1777	H4a1a1a	reconstructed	936.00	Knipper et al. 2017 Data	FASTA Metadata	10044G (MT-TG): SIDS (Unclear) 14582G (MT-ND6): LHON synergistic combo 14258A + 14582G (Reported: individually neutral variants causing LHON in combination)
WEHR_1375	EBAGe	Bronze Age	Germany	U	-1953	-1781	K1a3	reconstructed	29.10	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 3316A (MT-ND1): Diabetes / LHON / PEO (Unclear) 9055A (MT-ATP6): PD protective factor (Reported)
WEHR_1380	EBAGe	Bronze Age	Germany	M	-2021	-1895	K1a1b1g	reconstructed	160.70	Knipper et al. 2017 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15924G (MT-TT): LIMM (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
WEHR_1415adult	EBAGe	Bronze Age	Germany	F	-2008	-1883	H13a2b2a	reconstructed	559.50	Knipper et al. 2017 Data	FASTA Metadata
WEHR_1415child	EBAGe	Bronze Age	Germany	M	-2021	-1893	H13a2b2a	reconstructed	2022.20	Knipper et al. 2017 Data	FASTA Metadata
WEHR_1474	EBAGe	Bronze Age	Germany	M	-2029	-1916	V	reconstructed	1314.30	Knipper et al. 2017 Data	FASTA Metadata
WEHR_1564	EBAGe	Bronze Age	Germany	M	-2020	-1892	V	reconstructed	2467.10	Knipper et al. 2017 Data	FASTA Metadata
Ampack_1	BBC	Bronze Age	Germany	M	-2476	-2310	T2b33	reconstructed	1897.40	Knipper et al. 2017 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)