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C14 dated

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Table
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Name	Group	Epoch	Country	Sex	Year from	Year to	Haplogroup	Sequence source	Avg. coverage	Reference	Download	Map	Pathologies
LD270	CAIB	Copper Age	Portugal	F	-2564	-2578	U8a	fasta	131.10	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
COV20126	BAIB	Bronze Age	Spain	M	-1746	-1627	L2a1	fasta	84.70	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 15784C (MT-CYB): POAG - potential for association (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16390A (MT-CR): POAG - potential for association (Reported)
COV20125	BAIB	Bronze Age	Spain	U	-1886	-1702	U2e1	fasta	103.00	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
LU339	CAIB	Copper Age	Spain	F	-3007	-2871	H	fasta	102.20	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata
LU657	CAIB	Copper Age	Spain	U	-3500	-1700	U5b1	fasta	13.50	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
LD1174	CAIB	Copper Age	Portugal	F	-2577	-2456	U5b2	fasta	145.60	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12634G (MT-ND5): Thyroid Cancer Cell Line (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16270T (MT-CR): Melanoma patients (Reported)
LD903	BAIB	Bronze Age	Portugal	U	-2050	-1881	U3a1	fasta	38.30	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16390A (MT-CR): POAG - potential for association (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
Val05	NEIB	Neolithic	Spain	U	-3480	-3030	H1ay	fasta	125.80	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 9861C (MT-CO3): AD (Reported)
Val3.99	BAIB	Bronze Age	Spain	U	-1650	-1430	H3	fasta	14.40	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata
Val107	BAIB	Bronze Age	Spain	U	-1650	-1430	H1bm	fasta	42.10	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 9055A (MT-ATP6): PD protective factor (Reported)
Val145	BAIB	Bronze Age	Spain	U	-1650	-1430	H1bm	fasta	33.70	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 9055A (MT-ATP6): PD protective factor (Reported)
Val146	BAIB	Bronze Age	Spain	U	-1650	-1430	H1bm	fasta	57.70	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 9055A (MT-ATP6): PD protective factor (Reported)
Eiros1	BAIB	Bronze Age	Spain	U	-1499	-1310	V	fasta	72.10	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata
Eiros2	NEIB	Neolithic	Spain	U	-3636	-3381	U5b3	fasta	163.80	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported) 228A (MT-CR): Low VO2max response (Reported)
Rebolal	CAIB	Copper Age	Spain	U	-3500	-3181	K2b1	fasta	72.52	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13135A (MT-ND5): possible HCM susceptibility (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
Pxevi	CAIB	Copper Age	Spain	U	-3354	-3090	J2a1	fasta	167.80	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11251G (MT-ND4): Reduced risk of PD (Reported) 11253C (MT-ND4): LHON PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15257A (MT-CYB): LHON (Conflicting reports) 195C (MT-CR): BD-associated / melanoma pts (Reported) 295T (MT-CR): Low VO2max response (Reported) 4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported)
Pv517	CAIB	Copper Age	Spain	U	-3354	-3090	K2b1	fasta	145.60	Gonzalez-Fortes et al. 2019 Data	FASTA Metadata		11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13135A (MT-ND5): possible HCM susceptibility (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 9055A (MT-ATP6): PD protective factor (Reported)