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Name	Group	Epoch	Country	Sex	Year from	Year to	Haplogroup	Sequence source	Avg. coverage	Reference	Download	Pathologies
DA125	IAST	Iron Age	Kazakhstan	M	140	160	U2e2a1	bam	126.93	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA126	MAKa	Middle Ages	Kazakhstan	M	901	920	F2c1	bam	216.48	de Barros Damgaard et al. 2018 Data	FASTA Metadata	1005C (MT-RNR1): DEAF (Unclear) 11150A (MT-ND4): Found in a Multiple Sclerosis patient (Reported) 12338C (MT-ND5): DEAF1555 increased penetrance / LHON (Conflicting reports) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 16183C (MT-CR): Melanoma patients (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported)
DA127	IAKa	Iron Age	Kazakhstan	M	252	304	D4b1a2a1	bam	119.94	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 15951G (MT-TT): LHON / LHON modulator (Conflicting reports) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA128	MAKa	Middle Ages	Kazakhstan	F	1230	1230	D4o2a	bam	303.74	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA130	IAKa	Iron Age	Kazakhstan	M	-357	-284	G2a1	bam	57.70	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA134	IAST	Iron Age	Russia	M	0	100	I1	bam	66.88	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 15924G (MT-TT): LIMM (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 9966A (MT-CO3): LHON possible helper variant (Reported)
DA136	IAST	Iron Age	Russia	M	0	100	A+152+16362	<NA>	64.28	de Barros Damgaard et al. 2018 Data	Metadata
DA141	IAST	Iron Age	Russia	M	0	100	A+152+16362	bam	65.40	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA142	MAST	Middle Ages	Russia	M	0	100	J1c5a1	bam	312.57	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 185A (MT-CR): Low VO2max response (Reported) 295T (MT-CR): Low VO2max response (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 228A (MT-CR): Low VO2max response (Reported) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA143	IAST	Iron Age	Russia	F	0	100	U4b1a4	bam	80.56	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 499A (MT-CR): Endometriosis (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
DA144	IAST	Iron Age	Russia	M	0	100	H28	bam	81.39	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16192T (MT-CR): Melanoma patients (Reported)
DA145	IAST	Iron Age	Russia	M	0	100	U2e1h	bam	26.93	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 15043A (MT-CYB): MDD-associated (Reported)
DA146	IACA	Iron Age	Russia	F	300	1400	HV2a1	bam	44.95	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16217C (MT-CR): Endometriosis (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported)
DA160	IACA	Iron Age	Russia	F	300	1400	U4d3	bam	247.76	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 14577C (MT-ND6): MIDM (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 16183C (MT-CR): Melanoma patients (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 499A (MT-CR): Endometriosis (Reported)
DA161	IACA	Iron Age	Russia	M	300	1400	X2f	bam	33.98	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported)
DA162	IACA	Iron Age	Russia	M	300	1400	H13a2c	bam	772.73	de Barros Damgaard et al. 2018 Data	FASTA Metadata
DA164	IACA	Iron Age	Russia	F	300	1400	H5	bam	229.50	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 5549A (MT-TW): DEMCHO (Reported)
DA179	MAST	Middle Ages	Kazakhstan	M	1200	1400	D4	bam	317.38	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 4454C (MT-TM): Possible contributor to mito dysfunction / hypertension (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA189	MAST	Middle Ages	Russia	M	700	1000	J1b4	bam	167.46	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 295T (MT-CR): Low VO2max response (Reported) 3290C (MT-TL1): Poss. hypertension factor (Reported) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA191	SCHu	Iron Age	Hungary	F	-536	-526	H2a2	bam	3.33	de Barros Damgaard et al. 2018 Data	FASTA Metadata
DA195	SCHu	Iron Age	Hungary	F	-756	-727	H+16311	bam	130.03	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA198	SCHu	Iron Age	Hungary	M	-508	-498	H7a1	bam	74.71	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA199	MAHu	Middle Ages	Hungary	F	1224	1264	H1ba	bam	68.65	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16270T (MT-CR): Melanoma patients (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
DA201	IAKa	Iron Age	Kazakhstan	F	-171	-88	C4a1a+195	bam	111.11	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA202	IAST	Iron Age	Kazakhstan	F	-733	-690	U5a1	bam	20.96	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA203	MAST	Middle Ages	Kazakhstan	M	950	1250	G2a2	bam	139.30	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 4833G (MT-ND2): Diabetes helper mutation AD / PD (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA205	MAST	Middle Ages	Kazakhstan	F	950	1250	J1c	bam	206.67	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 15924G (MT-TT): LIMM (Reported) 185A (MT-CR): Low VO2max response (Reported) 295T (MT-CR): Low VO2max response (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 228A (MT-CR): Low VO2max response (Reported) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA207	MEST	Modern Era	Kazakhstan	M	1650	1850	H2a	bam	4.04	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA208	MEST	Modern Era	Kazakhstan	M	1650	1850	H1	bam	8.24	de Barros Damgaard et al. 2018 Data	FASTA Metadata	3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
DA220	IAKa	Iron Age	Kazakhstan	M	-350	-50	HV6	bam	111.75	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA221	IAKa	Iron Age	Kazakhstan	M	-790	-747	J1b1a1	bam	1184.38	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 295T (MT-CR): Low VO2max response (Reported) 2158C (MT-RNR2): Reduced risk PD (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported) 5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
DA223	IAKa	Iron Age	Kazakhstan	M	-403	-374	J1c5a	bam	740.55	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 185A (MT-CR): Low VO2max response (Reported) 295T (MT-CR): Low VO2max response (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 228A (MT-CR): Low VO2max response (Reported) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA224	MAST	Middle Ages	Kazakhstan	M	264	273	H	bam	6.92	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA227	IAKa	Iron Age	Kazakhstan	F	-350	-50	U5b2c	bam	11.45	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA228	MAST	Middle Ages	Kazakhstan	M	550	850	A15c	bam	24.16	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 5650A (MT-TA): Myopathy (Cfrm) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
DA229	IAST	Iron Age	Kazakhstan	M	-250	250	A8a1	bam	3.84	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported) 6962A (MT-CO1): Possible helper variant for 15927A (Reported)
DA230	MAKa	Middle Ages	Kazakhstan	M	750	950	F1b1e	bam	837.11	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16183C (MT-CR): Melanoma patients (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 6962A (MT-CO1): Possible helper variant for 15927A (Reported)
DA231	BAKa	Bronze Age	Kazakhstan	F	-1592	-1591	U2e1h	bam	248.30	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 14674C (MT-TE): Reversible COX deficiency myopathy (Cfrm) 16183C (MT-CR): Melanoma patients (Reported) 228A (MT-CR): Low VO2max response (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA243	IACA	Iron Age	Russia	M	300	400	W1	bam	829.81	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4454C (MT-TM): Possible contributor to mito dysfunction / hypertension (Reported) 5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
DA343	BASI	Bronze Age	Russia	M	-2647	-1776	D4j4	bam	899.55	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11696A (MT-ND4): LHON / LDYT / DEAF / hypertension helper mut. (Reported - possibly synergistic) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA353	BASI	Bronze Age	Russia	M	-2647	-1776	A+152+16362+16189	bam	97.02	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported) 8078A (MT-CO2): DEAF (Reported)
DA6	IASI	Iron Age	Russia	F	-900	-600	U2e2	bam	547.17	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
DA15	IAST	Iron Age	Kazakhstan	M	-755	-680	C4d	bam	215.25	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA17	IAST	Iron Age	Kazakhstan	M	-800	-773	H10	bam	123.92	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 5631A (MT-TA): Myopathy (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA18	IAST	Iron Age	Kazakhstan	F	-753	-681	U5b1c2	bam	329.34	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15894A (MT-TT): Gout (Reported) 16270T (MT-CR): Melanoma patients (Reported)
DA19	IAST	Iron Age	Kazakhstan	M	-801	-749	U7a4	bam	163.22	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 5628C (MT-TA): CPEO / DEAF enhancer / gout (Reported) 5650A (MT-TA): Myopathy (Cfrm) 7462T (MT-TS1): DEAF (Reported)
DA38	IAMo	Iron Age	Mongolia	F	-201	-148	D4b2b4	bam	900.33	de Barros Damgaard et al. 2018 Data	FASTA Metadata	195C (MT-CR): BD-associated / melanoma pts (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported)
DA47	IAKa	Iron Age	Kazakhstan	M	-168	-83	C4	bam	244.96	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 4454C (MT-TM): Possible contributor to mito dysfunction / hypertension (Reported) 489C (MT-CR): Low VO2max response (Reported) 9921A (MT-CO3): Possible LHON helper mutation (Reported)
DA50	IAKa	Iron Age	Kyrgyzstan	F	-550	-50	U5a1d2b	bam	162.85	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
DA53	IAKa	Iron Age	Kazakhstan	F	-453	-446	U5a1a1	bam	254.32	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15924G (MT-TT): LIMM (Reported) 16270T (MT-CR): Melanoma patients (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported)
DA55	IAKa	Iron Age	Kazakhstan	M	-89	-74	HV6	bam	268.68	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 5631A (MT-TA): Myopathy (Reported) 8249A (MT-CO2): Mitochondrial myopathy (Reported)
DA71	IAKa	Iron Age	Kazakhstan	F	252	308	A16	bam	1277.73	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
DA98	IAKy	Iron Age	Kyrgyzstan	F	61	144	J1d6	bam	271.09	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 295T (MT-CR): Low VO2max response (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported) 9041G (MT-ATP6): Patient with suspected mitochondrial disease (Reported as VUS)
DA111	BACz	Iron Age	Czech Republic	M	-836	-780	H6a1a	bam	118.07	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11253C (MT-ND4): LHON PD (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA118	MAKy	Middle Ages	Kyrgyzstan	F	1029	1049	F2g	bam	260.52	de Barros Damgaard et al. 2018 Data	FASTA Metadata	1005C (MT-RNR1): DEAF (Unclear) 12338C (MT-ND5): DEAF1555 increased penetrance / LHON (Conflicting reports) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
DA119	IASk	Iron Age	Slovakia	M	353	407	U4b3	bam	339.96	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 499A (MT-CR): Endometriosis (Reported)
DA129	IAKa	Iron Age	Kazakhstan	M	-427	-422	W3b	bam	320.85	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
DA139	IAST	Iron Age	Russia	F	0	100	U2e1h	bam	126.59	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16183C (MT-CR): Melanoma patients (Reported) 228A (MT-CR): Low VO2max response (Reported)
DA171	IABL	Iron Age	Lithuania	M	0	1000	H2a1	bam	24.68	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16176T (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
DA177	IAST	Iron Age	Kazakhstan	F	0	1000	D4j1b	bam	448.00	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11696A (MT-ND4): LHON / LDYT / DEAF / hypertension helper mut. (Reported - possibly synergistic) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA188	MAST	Middle Ages	Russia	M	776	793	I	bam	17.51	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15924G (MT-TT): LIMM (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
DA190	MAST	Middle Ages	Russia	M	649	680	U1a1c1	bam	88.42	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12397G (MT-ND5): PD / early onset (Reported)
DA197	SCHu	Iron Age	Hungary	M	-506	-505	H2a2a	bam	3.00	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported)
DA204	MAST	Middle Ages	Kazakhstan	M	897	925	A+152+16362+16189	bam	54.50	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16183C (MT-CR): Melanoma patients (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
DA206	IAST	Iron Age	Kazakhstan	M	133	254	HV13b	bam	110.29	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3290C (MT-TL1): Poss. hypertension factor (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported)
DA226	IAST	Iron Age	Kazakhstan	F	-250	450	U2e1h	bam	122.19	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16183C (MT-CR): Melanoma patients (Reported) 228A (MT-CR): Low VO2max response (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA356	BASI	Bronze Age	Russia	M	-2647	-1776	C4a1a3	bam	929.43	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported) 9139A (MT-ATP6): LHON (Reported - possibly synergistic)
DA361	BASI	Bronze Age	Russia	M	-2647	-1776	C4a1a3	bam	983.51	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA124	MAKa	Middle Ages	Kazakhstan	M	654	689	HV19	bam	116.36	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA92	IAST	Iron Age	Kazakhstan	M	-37	-28	J1b1a1+146	bam	313.88	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 146C (MT-CR): Absence of Endometriosis (Reported) 295T (MT-CR): Low VO2max response (Reported) 2158C (MT-RNR2): Reduced risk PD (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 462T (MT-CR): Low VO2max response (Reported) 489C (MT-CR): Low VO2max response (Reported) 5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
DA194	SCHu	Iron Age	Hungary	F	-408	-369	H2a2a1	bam	4.33	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 15924G (MT-TT): LIMM (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA222	MAKa	Middle Ages	Kazakhstan	M	750	950	A+152+16362	bam	586.30	de Barros Damgaard et al. 2018 Data	FASTA Metadata	1095C (MT-RNR1): SNHL (Unclear) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
DA2	IASI	Iron Age	Russia	M	-898	-835	N1a1a1a1	bam	224.27	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12280G (MT-TL2): Hypertension (Reported) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3336C (MT-ND1): Carotid atherosclerosis risk (Reported) 669C (MT-RNR1): DEAF (Reported)
DA3	IASI	Iron Age	Russia	F	-900	-600	N9a9	bam	368.29	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA4	IASI	Iron Age	Russia	M	-900	-600	H5a1+152	bam	255.65	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 3290C (MT-TL1): Poss. hypertension factor (Reported) 4395G (MT-TQ): Poss. hypertension factor (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 5703A (MT-TN): CPEO / MM (Cfrm) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA5	IASI	Iron Age	Russia	M	-900	-600	W1c	bam	898.81	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 5650A (MT-TA): Myopathy (Cfrm) 8932T (MT-ATP6): Prostate tumor / Neuromuscular disorder (Reported)
DA7	IASI	Iron Age	Russia	M	-900	-600	A8a1	bam	334.71	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 5650A (MT-TA): Myopathy (Cfrm)
DA8	IASI	Iron Age	Russia	F	-900	-600	U2e1h	bam	473.96	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 5703A (MT-TN): CPEO / MM (Cfrm) 7497A (MT-TS1): MM / EXIT (Cfrm)
DA9	IASI	Iron Age	Russia	F	-900	-600	F1b1b	bam	146.86	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 1095C (MT-RNR1): SNHL (Unclear) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA10	IAST	Iron Age	Kazakhstan	F	-600	-400	C4a1a	bam	485.37	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16270T (MT-CR): Melanoma patients (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported)
DA11	IAST	Iron Age	Kazakhstan	F	-766	-729	F1b1+@152	bam	282.70	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4454C (MT-TM): Possible contributor to mito dysfunction / hypertension (Reported) 5650A (MT-TA): Myopathy (Cfrm)
DA13	IAST	Iron Age	Kazakhstan	M	-752	-682	A+152+16362+16189	bam	525.80	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported) 7462T (MT-TS1): DEAF (Reported)
DA14	IAST	Iron Age	Kazakhstan	F	-753	-681	H101	bam	734.98	de Barros Damgaard et al. 2018 Data	FASTA Metadata	7462T (MT-TS1): DEAF (Reported)
DA16	IAST	Iron Age	Kazakhstan	M	-750	-683	U2e1'2'3	bam	209.41	de Barros Damgaard et al. 2018 Data	FASTA Metadata
DA20	IAST	Iron Age	Kazakhstan	M	-357	-342	C4a1a+195	bam	415.40	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 4440A (MT-TM): Mitochondrial myopathy (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA23	IAST	Middle Ages	Kazakhstan	M	1045	1095	F1b1b	bam	772.74	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16183C (MT-CR): Melanoma patients (Reported) 6962A (MT-CO1): Possible helper variant for 15927A (Reported)
DA26	IAST	Iron Age	Kazakhstan	F	-400	-100	U4a2	bam	331.72	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 499A (MT-CR): Endometriosis (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA27	IAST	Iron Age	Kazakhstan	M	349	368	C4b1	bam	618.31	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 4440A (MT-TM): Mitochondrial myopathy (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA28	IAST	Middle Ages	Kazakhstan	M	1200	1400	D4m2	bam	1900.58	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA29	IAST	Middle Ages	Kazakhstan	M	1200	1400	I1b	bam	814.14	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 15924G (MT-TT): LIMM (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 9133A (MT-ATP6): Patient with suspected mitochondrial disease (Reported as VUS) 9966A (MT-CO3): LHON possible helper variant (Reported)
DA30	IAST	Iron Age	Kazakhstan	M	-47	24	U4a2	bam	514.89	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 499A (MT-CR): Endometriosis (Reported)
DA31	IACA	Iron Age	Armenia	M	-1500	-700	HV0a	bam	254.11	de Barros Damgaard et al. 2018 Data	FASTA Metadata	295T (MT-CR): Low VO2max response (Reported)
DA35	IACA	Iron Age	Armenia	F	-1390	-1337	J1b1a1+146	bam	1372.45	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports) 146C (MT-CR): Absence of Endometriosis (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 2158C (MT-RNR2): Reduced risk PD (Reported) 489C (MT-CR): Low VO2max response (Reported) 5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
DA39	IAMo	Iron Age	Mongolia	M	-49	53	N9a2a	bam	670.32	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 5153G (MT-ND2): Recurrent pregnancy loss (Reported) 9966A (MT-CO3): LHON possible helper variant (Reported) 961C (MT-RNR1): DEAF / possibly LVNC-associated (Unclear)
DA41	IAMo	Iron Age	Mongolia	M	-347	-319	G3a3	bam	494.78	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16390A (MT-CR): POAG - potential for association (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA43	IAMo	Iron Age	Mongolia	M	-300	-100	D4a6	bam	439.54	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA45	IAMo	Iron Age	Mongolia	M	-156	-134	D4b2b2b	bam	3766.24	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 3290C (MT-TL1): Poss. hypertension factor (Reported) 4395G (MT-TQ): Poss. hypertension factor (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 5153G (MT-ND2): Recurrent pregnancy loss (Reported) 5703A (MT-TN): CPEO / MM (Cfrm) 5650A (MT-TA): Myopathy (Cfrm) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA48	IAKa	Iron Age	Kazakhstan	M	-550	-50	H4d	bam	23.35	de Barros Damgaard et al. 2018 Data	FASTA Metadata
DA49	IAKa	Iron Age	Kazakhstan	M	-356	-285	T2a1	bam	762.38	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11251G (MT-ND4): Reduced risk of PD (Reported) 10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 14687G (MT-TE): Mito myopathy w respiratory failure / intellectual disability (Reported) 15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported) 4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
DA51	IAKa	Iron Age	Kazakhstan	M	-361	-349	H2a1	bam	722.72	de Barros Damgaard et al. 2018 Data	FASTA Metadata
DA52	IAKa	Iron Age	Kazakhstan	M	403	434	G2a1d2	bam	1059.98	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12311C (MT-TL2): CPEO (Reported) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4833G (MT-ND2): Diabetes helper mutation AD / PD (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA54	IAKa	Iron Age	Kazakhstan	M	265	271	C4+152+16093	bam	140.36	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA56	IAKa	Iron Age	Kazakhstan	M	-159	-132	HV6	bam	429.36	de Barros Damgaard et al. 2018 Data	FASTA Metadata	310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA57	IAKa	Iron Age	Kazakhstan	M	-169	-90	D4j8	bam	621.21	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11696A (MT-ND4): LHON / LDYT / DEAF / hypertension helper mut. (Reported - possibly synergistic) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 5650A (MT-TA): Myopathy (Cfrm) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA58	IAKa	Iron Age	Kazakhstan	M	-166	-89	W1c	bam	730.40	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
DA59	IAKa	Iron Age	Kazakhstan	M	-349	-313	D4j8	bam	307.45	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11696A (MT-ND4): LHON / LDYT / DEAF / hypertension helper mut. (Reported - possibly synergistic) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA385	IAKa	Iron Age	Kazakhstan	M	397	570	H13a2a	bam	369.92	de Barros Damgaard et al. 2018 Data	FASTA Metadata	195C (MT-CR): BD-associated / melanoma pts (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported)
DA65	IAKa	Iron Age	Kazakhstan	M	382	433	N9a9	bam	116.30	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA66	IAKa	Iron Age	Kazakhstan	F	430	492	H6b2	bam	390.40	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16300G (MT-CR): BD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA68	IAKa	Iron Age	Kazakhstan	F	557	615	M11a	bam	396.73	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14340T (MT-ND6): SNHL (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 489C (MT-CR): Low VO2max response (Reported) 8108G (MT-CO2): SNHL (Reported)
DA69	IAKa	Iron Age	Kazakhstan	F	349	368	U5b2a1a2	bam	329.73	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 13637G (MT-ND5): Possible LHON factor (Reported) 150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports) 15924G (MT-TT): LIMM (Reported) 5452T (MT-ND2): Progressive Encephalomyopathy (Reported)
DA70	IAKa	Iron Age	Kazakhstan	F	60	143	C4a1a+195	bam	284.87	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 195C (MT-CR): BD-associated / melanoma pts (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA72	IAKa	Iron Age	Kazakhstan	F	264	274	M10a1+16129	bam	367.14	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14502C (MT-ND6): LHON (Reported - possibly synergistic) 146C (MT-CR): Absence of Endometriosis (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3253C (MT-TL1): Maternally inherited hypertension (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA73	IAKa	Iron Age	Kazakhstan	M	255	301	G2a1	bam	493.12	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 4833G (MT-ND2): Diabetes helper mutation AD / PD (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA74	IAKa	Iron Age	Kazakhstan	M	385	435	H7b	bam	442.00	de Barros Damgaard et al. 2018 Data	FASTA Metadata
DA80	IAKa	Iron Age	Kazakhstan	F	257	297	A1a	bam	536.14	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
DA81	IAKa	Iron Age	Kazakhstan	M	177	190	A16	bam	1093.76	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4440A (MT-TM): Mitochondrial myopathy (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
DA82	IAKa	Iron Age	Kazakhstan	F	83	177	K2a5	bam	1269.22	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 16093C (MT-CR): Cyclic Vomiting Syndrome (Reported) 9055A (MT-ATP6): PD protective factor (Reported)
DA85	IAKa	Iron Age	Kazakhstan	M	170	194	U4a2	bam	1675.64	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 499A (MT-CR): Endometriosis (Reported)
DA86	MAKy	Middle Ages	Kyrgyzstan	M	424	474	C4b1	bam	337.51	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA87	MAST	Middle Ages	Kazakhstan	M	640	692	A+152+16362	bam	124.80	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
DA89	MAST	Middle Ages	Kazakhstan	M	659	712	A14	bam	173.40	de Barros Damgaard et al. 2018 Data	FASTA Metadata	12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 663G (MT-RNR1): Coronary atherosclerosis risk (Reported) 735G (MT-RNR1): DEAF (Reported)
DA93	MAST	Middle Ages	Kazakhstan	M	727	737	D4j8	bam	200.59	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 1095C (MT-RNR1): SNHL (Unclear) 11696A (MT-ND4): LHON / LDYT / DEAF / hypertension helper mut. (Reported - possibly synergistic) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA94	MAST	Middle Ages	Kazakhstan	M	700	900	Z1a1	bam	123.58	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 15784C (MT-CYB): POAG - potential for association (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA95	IAST	Iron Age	Kazakhstan	M	259	282	D4b1	bam	348.10	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 1095C (MT-RNR1): SNHL (Unclear) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 15951G (MT-TT): LHON / LHON modulator (Conflicting reports) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA96	IAKy	Iron Age	Kyrgyzstan	M	259	281	D4j5	bam	564.52	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 11696A (MT-ND4): LHON / LDYT / DEAF / hypertension helper mut. (Reported - possibly synergistic) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 14668T (MT-ND6): Depressive Disorder associated (Reported) 15043A (MT-CYB): MDD-associated (Reported) 3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4883T (MT-ND2): Glaucoma (Conflicting reports) 489C (MT-CR): Low VO2max response (Reported) 8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
DA99	MAKy	Middle Ages	Kyrgyzstan	F	1161	1255	C4a2c	bam	358.12	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 13967T (MT-ND5): Possible LHON factor (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3394C (MT-ND1): LHON / Diabetes / CPTdeficiency / high altitude adaptation (Reported / Population-dependent) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA100	IAKy	Iron Age	Kyrgyzstan	M	255	300	C4b1	bam	320.14	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA101	IAKy	Iron Age	Kyrgyzstan	M	214	261	U5a1b1e	bam	1806.03	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11467G (MT-ND4): Altered brain pH / sCJD patients (Reported) 12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported) 12372A (MT-ND5): Altered brain pH / sCJD patients (Reported) 16192T (MT-CR): Melanoma patients (Reported) 16270T (MT-CR): Melanoma patients (Reported)
DA104	IAKy	Iron Age	Kyrgyzstan	F	100	500	F1b1+@152	bam	224.03	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16183C (MT-CR): Melanoma patients (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 6962A (MT-CO1): Possible helper variant for 15927A (Reported)
DA105	IAKy	Iron Age	Kyrgyzstan	M	134	219	F1b1+@152	bam	189.88	de Barros Damgaard et al. 2018 Data	FASTA Metadata	16183C (MT-CR): Melanoma patients (Reported) 16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 6962A (MT-CO1): Possible helper variant for 15927A (Reported)
DA106	MAKy	Middle Ages	Kyrgyzstan	M	1170	1171	C4b1a	bam	693.83	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 146C (MT-CR): Absence of Endometriosis (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)
DA112	BACz	Iron Age	Czech Republic	F	-729	-693	HV0+195	bam	362.87	de Barros Damgaard et al. 2018 Data	FASTA Metadata	195C (MT-CR): BD-associated / melanoma pts (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA116	MAKy	Middle Ages	Kyrgyzstan	F	1156	1224	G2a+152	bam	766.10	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported) 4833G (MT-ND2): Diabetes helper mutation AD / PD (Reported) 489C (MT-CR): Low VO2max response (Reported)
DA117	MEKy	Modern Era	Kyrgyzstan	M	1678	1696	H6a1b	bam	301.35	de Barros Damgaard et al. 2018 Data	FASTA Metadata	195C (MT-CR): BD-associated / melanoma pts (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA121	IAST	Iron Age	Kazakhstan	F	264	273	H6a1a	bam	177.93	de Barros Damgaard et al. 2018 Data	FASTA Metadata	11253C (MT-ND4): LHON PD (Reported) 310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
DA123	MAST	Middle Ages	Kazakhstan	F	-100	800	C4a1	bam	448.88	de Barros Damgaard et al. 2018 Data	FASTA Metadata	10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK) 12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported) 15043A (MT-CYB): MDD-associated (Reported) 16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported) 3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker) 489C (MT-CR): Low VO2max response (Reported)