I5207
|
LBK |
Neolithic |
Austria |
M |
-5500 |
-4500 |
H67 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
DA125
|
IAST |
Iron Age |
Kazakhstan |
M |
140 |
160 |
U2e2a1 |
bam
|
126.93
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
RISE507
|
BARu |
Bronze Age |
Russia |
F |
-3322 |
-2923 |
U5a1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I3596
|
BBC |
Copper Age |
Germany |
M |
-2300 |
-2150 |
H+16129 |
bam
|
119.37
|
|
FASTA
Metadata
|
|
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I6590
|
BBC |
Copper Age |
Germany |
F |
-2500 |
-2000 |
X2c1 |
bam
|
509.04
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I5208
|
LBK |
Neolithic |
Austria |
F |
-5500 |
-4500 |
K1b1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5834
|
BBC |
Copper Age |
Germany |
F |
-2500 |
-2000 |
W5 |
bam
|
275.62
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I5373
|
BABI |
Bronze Age |
Great Britain |
M |
-2194 |
-1980 |
X2b+226 |
bam
|
214.55
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported)
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
8393T (MT-ATP8): Reversible brain pseudoatrophy (Reported)
|
I1496
|
LBK |
Neolithic |
Hungary |
M |
-5211 |
-4992 |
K1a3a3 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
RISE508
|
BARu |
Bronze Age |
Russia |
F |
-3331 |
-2935 |
U5a1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I2601
|
BABI |
Bronze Age |
Great Britain |
F |
-1955 |
-1750 |
U5a1b1a |
bam
|
19.73
|
|
FASTA
Metadata
|
|
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0708
|
NENE |
Neolithic |
Turkey |
M |
-6500 |
-6200 |
N1b1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
16390A (MT-CR): POAG - potential for association (Reported)
-
8836G (MT-ATP6): LHON (Reported)
|
DA126
|
MAKa |
Middle Ages |
Kazakhstan |
M |
901 |
920 |
F2c1 |
bam
|
216.48
|
|
FASTA
Metadata
|
|
-
1005C (MT-RNR1): DEAF (Unclear)
-
11150A (MT-ND4): Found in a Multiple Sclerosis patient (Reported)
-
12338C (MT-ND5): DEAF1555 increased penetrance / LHON (Conflicting reports)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
4440A (MT-TM): Mitochondrial myopathy (Reported)
|
I3607
|
BBC |
Copper Age |
Germany |
M |
-2350 |
-2250 |
W3a1 |
bam
|
15.11
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15784C (MT-CYB): POAG - potential for association (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I3494
|
BAIB |
Bronze Age |
Spain |
M |
-1920 |
-1753 |
J1c1b |
bam
|
641.00
|
|
Metadata
|
|
|
I0746
|
NENE |
Neolithic |
Turkey |
M |
-6067 |
-5892 |
K1a or K1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I2602
|
BABI |
Bronze Age |
Great Britain |
M |
-1892 |
-1699 |
U5b2b |
bam
|
112.84
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
12634G (MT-ND5): Thyroid Cancer Cell Line (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I11303
|
NEIB |
Neolithic |
Spain |
F |
-3400 |
-2500 |
H1j |
bam
|
28.10
|
|
Metadata
|
|
|
I2463
|
BABI |
Bronze Age |
Great Britain |
F |
-1925 |
-1700 |
J1c3+189 |
bam
|
250.88
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I1495
|
LDN |
Neolithic |
Hungary |
M |
-4491 |
-4357 |
N1a1a1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I4914
|
HGS |
Mesolithic |
Serbia |
M |
-6355 |
-5990 |
U5a1c1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I2462
|
BABI |
Bronze Age |
Great Britain |
F |
-2128 |
-1891 |
U5a1d2a |
bam
|
274.64
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I4665
|
HGS |
Mesolithic |
Serbia |
F |
-6205 |
-5907 |
J2b1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I1099
|
NENE |
Neolithic |
Turkey |
M |
-6500 |
-6200 |
T2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I4666
|
HGS |
Mesolithic |
Serbia |
M |
-6222 |
-5912 |
H40 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I2612
|
BABI |
Bronze Age |
Great Britain |
F |
-2464 |
-2208 |
U5b2b2 |
bam
|
373.29
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
12634G (MT-ND5): Thyroid Cancer Cell Line (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I1102
|
NENE |
Neolithic |
Turkey |
M |
-6500 |
-6200 |
K1a3a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I5405
|
HGS |
Mesolithic |
Serbia |
F |
-5836 |
-5632 |
HV |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5658
|
BBC |
Copper Age |
Germany |
F |
-2500 |
-2000 |
T2b+152 |
bam
|
514.19
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I1416
|
PPNE |
Neolithic |
Jordan |
M |
-8300 |
-7900 |
None |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I1581
|
NENE |
Neolithic |
Turkey |
F |
-6500 |
-6200 |
U3 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I1699
|
PPNE |
Neolithic |
Jordan |
F |
-6800 |
-6700 |
R0a2 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
DA127
|
IAKa |
Iron Age |
Kazakhstan |
M |
252 |
304 |
D4b1a2a1 |
bam
|
119.94
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
14668T (MT-ND6): Depressive Disorder associated (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
15951G (MT-TT): LHON / LHON modulator (Conflicting reports)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4883T (MT-ND2): Glaucoma (Conflicting reports)
-
489C (MT-CR): Low VO2max response (Reported)
-
8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
|
I2421
|
BABI |
Bronze Age |
Great Britain |
M |
-1930 |
-1759 |
U5a1a2a |
bam
|
232.06
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0723
|
NENE |
Neolithic |
Turkey |
M |
-6400 |
-5600 |
X2m2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2609
|
BABI |
Bronze Age |
Great Britain |
F |
-2022 |
-1771 |
K2a |
bam
|
163.71
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I2037
|
LBK |
Neolithic |
Germany |
M |
-5210 |
-5002 |
H1e |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I1709
|
PPNE |
Neolithic |
Jordan |
M |
-8300 |
-7900 |
U8b1a |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I7630
|
BABI |
Bronze Age |
Great Britain |
M |
-1879 |
-1691 |
U5a |
bam
|
4.57
|
|
FASTA
Metadata
|
|
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
|
I1710
|
PPNE |
Neolithic |
Jordan |
M |
-7733 |
-7526 |
T1a2 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I3997
|
BAIB |
Bronze Age |
Spain |
M |
-1864 |
-1618 |
K1a2b |
bam
|
29.70
|
|
Metadata
|
|
|
I1727
|
PPNE |
Neolithic |
Jordan |
M |
-8300 |
-7900 |
T1a2 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
DA128
|
MAKa |
Middle Ages |
Kazakhstan |
F |
1230 |
1230 |
D4o2a |
bam
|
303.74
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
14668T (MT-ND6): Depressive Disorder associated (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4883T (MT-ND2): Glaucoma (Conflicting reports)
-
489C (MT-CR): Low VO2max response (Reported)
-
8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
|
DA130
|
IAKa |
Iron Age |
Kazakhstan |
M |
-357 |
-284 |
G2a1 |
bam
|
57.70
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I5661
|
BBC |
Copper Age |
Germany |
M |
-2500 |
-2000 |
K1b1b1 |
bam
|
83.32
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
14063C (MT-ND5): Potentially functional variant cosegregating with LHON3635A (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I1109
|
NEBA |
Neolithic |
Bulgaria |
F |
-5800 |
-5400 |
J2b1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5441
|
BABI |
Bronze Age |
Great Britain |
M |
-1938 |
-1744 |
H1+16239 |
bam
|
199.01
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
I0014
|
HGN |
Mesolithic |
Sweden |
F |
-5877 |
-5629 |
U5a2d |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I5663
|
BBC |
Copper Age |
Germany |
M |
-2500 |
-2000 |
U5a2+16294 |
bam
|
283.20
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I0551
|
SMC |
Neolithic |
Germany |
M |
-3400 |
-3025 |
U3a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16390A (MT-CR): POAG - potential for association (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
I1295
|
NEBA |
Neolithic |
Bulgaria |
M |
-5800 |
-5400 |
J1c |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I2461
|
BABI |
Bronze Age |
Great Britain |
F |
-2500 |
-2140 |
H5c |
bam
|
357.81
|
|
FASTA
Metadata
|
|
|
I0559
|
BAC |
Neolithic |
Germany |
M |
-3654 |
-3527 |
HV |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I1296
|
NEBA |
Neolithic |
Bulgaria |
M |
-5800 |
-5400 |
U5a2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I2637
|
NEBI |
Neolithic |
Great Britain |
M |
-3629 |
-3370 |
K1b1a1 |
bam
|
172.64
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13967T (MT-ND5): Possible LHON factor (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I2618
|
BABI |
Bronze Age |
Great Britain |
M |
-2134 |
-1950 |
H1bs |
bam
|
706.46
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0103
|
CWC |
Neolithic |
Germany |
F |
-2578 |
-2468 |
W6a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I2216
|
NEBA |
Neolithic |
Bulgaria |
F |
-5800 |
-5400 |
J2b1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5377
|
BABI |
Bronze Age |
Great Britain |
M |
-1894 |
-1694 |
T2b |
bam
|
243.84
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I5383
|
BABI |
Bronze Age |
Great Britain |
F |
-1090 |
-900 |
J1c5f |
bam
|
137.67
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
15924G (MT-TT): LIMM (Reported)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I8571
|
BAIB |
Bronze Age |
Spain |
M |
-1800 |
-1000 |
K1a2c |
bam
|
48.50
|
|
Metadata
|
|
|
I7639
|
BABI |
Bronze Age |
Great Britain |
F |
-2031 |
-1665 |
U5a1 |
bam
|
1.56
|
|
FASTA
Metadata
|
|
|
I3879
|
NEBA |
Neolithic |
Bulgaria |
M |
-5800 |
-5400 |
H |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I0070
|
MIC |
Bronze Age |
Greece |
M |
-2400 |
-1700 |
H13a1a |
<NA>
|
<NA>
|
|
Metadata
|
|
|
DA134
|
IAST |
Iron Age |
Russia |
M |
0 |
100 |
I1 |
bam
|
66.88
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
9966A (MT-CO3): LHON possible helper variant (Reported)
|
I2639
|
BABI |
Bronze Age |
Great Britain |
F |
-1600 |
-1430 |
T2e1a |
bam
|
1051.40
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I2796
|
NEBI |
Neolithic |
Great Britain |
M |
-3705 |
-3535 |
H3 |
bam
|
232.16
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I7570
|
BABI |
Bronze Age |
Great Britain |
M |
-1735 |
-1531 |
T2b4+152 |
bam
|
88.74
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
RISE61
|
NESC |
Neolithic |
Denmark |
M |
-2851 |
-2492 |
J1c4 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
Rev5
|
NEGr |
Neolithic |
Greece |
F |
-6438 |
-6264 |
X2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5656
|
BBC |
Copper Age |
Germany |
U |
-2500 |
-2000 |
T2g2 |
bam
|
214.36
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I7575
|
BABI |
Bronze Age |
Great Britain |
M |
-1263 |
-1043 |
U5a1d1 |
bam
|
163.31
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I7577
|
BABI |
Bronze Age |
Great Britain |
M |
-1386 |
-1123 |
U5a1a1 |
bam
|
146.15
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I3708
|
NEGr |
Neolithic |
Greece |
F |
-5500 |
-3700 |
T1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I3709
|
NEGr |
Neolithic |
Greece |
F |
-3990 |
-3804 |
K1b1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I3920
|
NEGr |
Neolithic |
Greece |
F |
-3933 |
-3706 |
H |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
DA136
|
IAST |
Iron Age |
Russia |
M |
0 |
100 |
A+152+16362 |
<NA>
|
64.28
|
|
Metadata
|
|
|
I7580
|
BABI |
Bronze Age |
Great Britain |
F |
-1256 |
-1018 |
U5b2a1a |
bam
|
217.86
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
|
RISE392
|
BARu |
Bronze Age |
Russia |
M |
-2126 |
-1896 |
J2b1a2a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
15812A (MT-CYB): LHON (Reported / Secondary)
-
295T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I3604
|
BBC |
Copper Age |
Germany |
M |
-2350 |
-2250 |
HV9 |
bam
|
11.45
|
|
FASTA
Metadata
|
|
|
I2318
|
NEGr |
Neolithic |
Greece |
F |
-4043 |
-3947 |
H2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I1926
|
TRP |
Neolithic |
Ukraine |
M |
-3931 |
-3640 |
H5a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I7688
|
BAIB |
Bronze Age |
Portugal |
F |
-1200 |
-700 |
H3ap |
bam
|
49.60
|
|
Metadata
|
|
|
RISE577
|
UNC |
Bronze Age |
Czech Republic |
F |
-2300 |
-1800 |
T2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I5401
|
HGS |
Mesolithic |
Serbia |
M |
-7076 |
-6699 |
U5a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
16390A (MT-CR): POAG - potential for association (Reported)
|
I7626
|
BABI |
Bronze Age |
Great Britain |
F |
-1395 |
-1130 |
T2b |
bam
|
165.27
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I2111
|
TRP |
Neolithic |
Ukraine |
M |
-3758 |
-3636 |
HV |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
RISE349
|
BAHu |
Bronze Age |
Hungary |
F |
-2034 |
-1784 |
T2b3 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I6561
|
NEUk |
Neolithic |
Ukraine |
M |
-4045 |
-3974 |
H2a1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I0048
|
LBK |
Neolithic |
Germany |
M |
-5210 |
-5002 |
K1a26 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I7627
|
BABI |
Bronze Age |
Great Britain |
F |
-1410 |
-1222 |
U4a2 |
bam
|
226.03
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I5882
|
NEUk |
Neolithic |
Ukraine |
F |
-3264 |
-2929 |
U5a2a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5523
|
BBC |
Copper Age |
Germany |
F |
-2500 |
-2000 |
K1b1a1+199 |
bam
|
113.04
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13967T (MT-ND5): Possible LHON factor (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I5019
|
BBC |
Copper Age |
Germany |
F |
-2500 |
-2000 |
K1b1a1 |
bam
|
68.25
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13967T (MT-ND5): Possible LHON factor (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I7628
|
BABI |
Bronze Age |
Great Britain |
M |
-1208 |
-978 |
T1a1 |
bam
|
26.04
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I5884
|
NEUk |
Neolithic |
Ukraine |
M |
-2890 |
-2696 |
U5a2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I7579
|
BABI |
Bronze Age |
Great Britain |
F |
-1496 |
-1300 |
U5b2a1a |
bam
|
182.54
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I7687
|
BAIB |
Bronze Age |
Portugal |
M |
-1200 |
-700 |
V |
bam
|
44.70
|
|
Metadata
|
|
|
I5885
|
NEUk |
Neolithic |
Ukraine |
F |
-6392 |
-5927 |
U5b2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I3082
|
BABI |
Bronze Age |
Great Britain |
M |
-1498 |
-1394 |
H1an1a |
bam
|
199.91
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4454C (MT-TM): Possible contributor to mito dysfunction / hypertension (Reported)
|
DA141
|
IAST |
Iron Age |
Russia |
M |
0 |
100 |
A+152+16362 |
bam
|
65.40
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
|
I1733
|
HGE |
Mesolithic |
Ukraine |
F |
-9000 |
-7500 |
U4b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5524
|
BBC |
Copper Age |
Germany |
F |
-2500 |
-2000 |
H72 |
bam
|
300.85
|
|
FASTA
Metadata
|
|
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I7574
|
BABI |
Bronze Age |
Great Britain |
F |
-1406 |
-1230 |
H1a3 |
bam
|
203.88
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I1734
|
HGE |
Mesolithic |
Ukraine |
M |
-7446 |
-7058 |
U5b2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
MA1
|
HGE |
Upper Paleolithic |
Russia |
M |
-22570 |
-22140 |
None |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
|
I4305
|
MLN |
Neolithic |
France |
F |
-4825 |
-4616 |
T2b3+151 |
bam
|
277.19
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I4308
|
MLN |
Neolithic |
France |
F |
-3501 |
-3112 |
U3a1 |
bam
|
16.06
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
16390A (MT-CR): POAG - potential for association (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
I1737
|
HGE |
Mesolithic |
Ukraine |
F |
-8540 |
-8301 |
U5a2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I3717
|
NEUk |
Neolithic |
Ukraine |
M |
-5460 |
-5218 |
U5a2a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
RISE374
|
BAHu |
Bronze Age |
Hungary |
M |
-1866 |
-1619 |
T2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I5526
|
BBC |
Copper Age |
Germany |
F |
-2500 |
-2000 |
H72 |
bam
|
751.70
|
|
FASTA
Metadata
|
|
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I7571
|
BABI |
Bronze Age |
Great Britain |
M |
-1448 |
-1259 |
J1c1 |
bam
|
117.06
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3394C (MT-ND1): LHON / Diabetes / CPTdeficiency / high altitude adaptation (Reported / Population-dependent)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I3718
|
NEUk |
Neolithic |
Ukraine |
M |
-5345 |
-5215 |
U5a1b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I0013
|
HGN |
Mesolithic |
Sweden |
M |
-5964 |
-5638 |
U5a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I4081
|
HGS |
Mesolithic |
Romania |
M |
-7580 |
-7190 |
H13 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I7572
|
BABI |
Bronze Age |
Great Britain |
M |
-1510 |
-1302 |
H13a1a |
bam
|
52.42
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I5020
|
BBC |
Copper Age |
Germany |
F |
-2457 |
-2205 |
H2a1e |
bam
|
151.53
|
|
FASTA
Metadata
|
|
|
I0518
|
NEBI |
Neolithic |
Great Britain |
M |
-3360 |
-3100 |
K1a3a1 |
bam
|
25.79
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I5037
|
EBACz |
Bronze Age |
Czech Republic |
M |
-2300 |
-1900 |
K1a+150 |
bam
|
50.19
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
DA142
|
MAST |
Middle Ages |
Russia |
M |
0 |
100 |
J1c5a1 |
bam
|
312.57
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I8136
|
BAIB |
Bronze Age |
Spain |
F |
-1606 |
-1418 |
K1b1a1 |
bam
|
54.30
|
|
Metadata
|
|
|
I4111
|
NEUk |
Neolithic |
Ukraine |
F |
-4722 |
-4548 |
U4d |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5044
|
EBACz |
Bronze Age |
Czech Republic |
F |
-2300 |
-1900 |
K1b1a |
bam
|
197.62
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I0519
|
NEBI |
Neolithic |
Great Britain |
M |
-3360 |
-3100 |
X2b+226 |
bam
|
441.62
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
8393T (MT-ATP8): Reversible brain pseudoatrophy (Reported)
|
I4114
|
NEUk |
Neolithic |
Ukraine |
M |
-5473 |
-5329 |
U5a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I7689
|
BAIB |
Bronze Age |
Portugal |
F |
-2200 |
-1700 |
H1+16311 |
bam
|
11.10
|
|
Metadata
|
|
|
I5875
|
NEUk |
Neolithic |
Ukraine |
M |
-5291 |
-5060 |
U4a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I3068
|
NEBI |
Neolithic |
Great Britain |
M |
-3692 |
-3522 |
T2c1d1 |
bam
|
541.45
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
-
6261A (MT-CO1): Prostate Cancer / LHON (Reported)
|
I5883
|
NEUk |
Neolithic |
Ukraine |
M |
-5208 |
-5003 |
U4a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I4582
|
HGS |
Mesolithic |
Romania |
F |
-7021 |
-6473 |
K1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I0432
|
BARu |
Bronze Age |
Russia |
M |
-2925 |
-2491 |
U5a1c |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I5116
|
CAHu |
Copper Age |
Hungary |
F |
-3400 |
-3000 |
W |
bam
|
9.19
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I2605
|
NEBI |
Neolithic |
Great Britain |
F |
-3631 |
-2944 |
J1c6 |
bam
|
291.74
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I5890
|
NEUk |
Neolithic |
Ukraine |
M |
-5286 |
-5062 |
U5a1b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
DA143
|
IAST |
Iron Age |
Russia |
F |
0 |
100 |
U4b1a4 |
bam
|
80.56
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
499A (MT-CR): Endometriosis (Reported)
-
663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
|
I7692
|
BAIB |
Bronze Age |
Portugal |
F |
-2200 |
-1700 |
U5b1+16189+@16192 |
bam
|
7.89
|
|
Metadata
|
|
|
I5891
|
NEUk |
Neolithic |
Ukraine |
M |
-5465 |
-5310 |
U4d |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5892
|
NEUk |
Neolithic |
Ukraine |
M |
-5301 |
-4982 |
U4a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5118
|
CAHu |
Copper Age |
Hungary |
M |
-3400 |
-3000 |
H+16129 |
bam
|
259.05
|
|
FASTA
Metadata
|
|
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2606
|
NEBI |
Neolithic |
Great Britain |
M |
-3330 |
-2900 |
K1a+195 |
bam
|
93.66
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I0433
|
YAM |
Bronze Age |
Russia |
M |
-5200 |
-4000 |
U5a1i |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9058G (MT-ATP6): Patients with (1) LVNC cardiomyopathy / (2) autism / intellectual disability / epilepsy (Reported as (1) possible association or as (2) benign)
|
E09538
|
BBC |
Copper Age |
Germany |
M |
-2464 |
-2210 |
J1c |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I6751
|
NEBI |
Neolithic |
Great Britain |
F |
-3755 |
-3660 |
U5b1+16189+@16192 |
bam
|
417.88
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I6759
|
NEBI |
Neolithic |
Great Britain |
M |
-3650 |
-3522 |
J1c1 |
bam
|
491.39
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3394C (MT-ND1): LHON / Diabetes / CPTdeficiency / high altitude adaptation (Reported / Population-dependent)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
-
6150A (MT-CO1): Prostate Cancer / enriched in POAG cohort (Reported)
|
I7691
|
BAIB |
Bronze Age |
Portugal |
M |
-2200 |
-1700 |
J1c1 |
bam
|
30.80
|
|
Metadata
|
|
|
I5893
|
NEUk |
Neolithic |
Ukraine |
M |
-5374 |
-5226 |
U5a2a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I6762
|
NEBI |
Neolithic |
Great Britain |
M |
-4000 |
-3300 |
K1a1b1 |
bam
|
165.31
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
114T (MT-CR): BD-associated (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
E09569
|
BBC |
Copper Age |
Germany |
M |
-2396 |
-2148 |
J1c2 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I1736
|
NEUk |
Neolithic |
Ukraine |
F |
-6248 |
-6070 |
U5b2b1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I6761
|
NEBI |
Neolithic |
Great Britain |
F |
-3650 |
-3400 |
K1a+195 |
bam
|
186.26
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I5515
|
BABI |
Bronze Age |
Great Britain |
M |
-2034 |
-1775 |
H3+16311 |
bam
|
44.57
|
|
FASTA
Metadata
|
|
|
I3713
|
NEUk |
Neolithic |
Ukraine |
M |
-5190 |
-4911 |
U4b1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I7042
|
BAHu |
Bronze Age |
Hungary |
M |
-2500 |
-2200 |
H |
bam
|
503.18
|
|
FASTA
Metadata
|
|
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
3236G (MT-TL1): Sporadic bilateral optic neuropathy (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I3715
|
NEUk |
Neolithic |
Ukraine |
M |
-5636 |
-5521 |
U2e1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I11306
|
NEIB |
Neolithic |
Spain |
F |
-3400 |
-2500 |
J2b1a2 |
bam
|
256.00
|
|
Metadata
|
|
|
I5868
|
NEUk |
Neolithic |
Ukraine |
M |
-5467 |
-5315 |
U4d |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5473
|
BABI |
Bronze Age |
Great Britain |
M |
-2400 |
-2100 |
U5b |
bam
|
1.66
|
|
FASTA
Metadata
|
|
-
16270T (MT-CR): Melanoma patients (Reported)
|
I6482
|
BBC |
Copper Age |
Germany |
F |
-2500 |
-2000 |
U4d2 |
bam
|
4.38
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
5567C (MT-TW): Myopathy (Reported)
|
I0358
|
SRU |
Bronze Age |
Russia |
F |
-1906 |
-1631 |
H6a1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11253C (MT-ND4): LHON PD (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I6133
|
NEUk |
Neolithic |
Ukraine |
F |
-6500 |
-4000 |
U5b2a1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
|
I1732
|
NEUk |
Neolithic |
Ukraine |
F |
-5364 |
-5213 |
U4b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I5516
|
BABI |
Bronze Age |
Great Britain |
M |
-1866 |
-1615 |
T2a1b1a1b |
bam
|
79.93
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
14687G (MT-TE): Mito myopathy w respiratory failure / intellectual disability (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I1738
|
NEUk |
Neolithic |
Ukraine |
M |
-5473 |
-5326 |
U5a2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
DA144
|
IAST |
Iron Age |
Russia |
M |
0 |
100 |
H28 |
bam
|
81.39
|
|
FASTA
Metadata
|
|
-
16192T (MT-CR): Melanoma patients (Reported)
|
I6481
|
BBC |
Copper Age |
Germany |
M |
-2500 |
-2000 |
U5a1a1 |
bam
|
82.94
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I5530
|
BBC |
Copper Age |
Germany |
M |
-2500 |
-2000 |
K1b1a1 |
bam
|
62.23
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13967T (MT-ND5): Possible LHON factor (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I2567
|
BABI |
Bronze Age |
Great Britain |
M |
-2275 |
-1884 |
U4a1a |
bam
|
372.89
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
499A (MT-CR): Endometriosis (Reported)
-
961C (MT-RNR1): DEAF / possibly LVNC-associated (Unclear)
|
I3757
|
IAIB |
Iron Age |
Spain |
F |
-400 |
-300 |
J1c1 |
bam
|
55.10
|
|
Metadata
|
|
|
I7203
|
UNC |
Bronze Age |
Czech Republic |
M |
-2200 |
-1700 |
H1 |
bam
|
13.12
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
I0047
|
UNC |
Bronze Age |
Germany |
F |
-2111 |
-1891 |
V9 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
14841G (MT-CYB): LHON helper mut. (Reported)
|
I2569
|
BABI |
Bronze Age |
Great Britain |
M |
-2139 |
-1915 |
K1a3a |
bam
|
220.51
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3316A (MT-ND1): Diabetes / LHON / PEO (Unclear)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I3496
|
IAIB |
Iron Age |
Spain |
M |
-300 |
-200 |
H1e1a |
bam
|
103.00
|
|
Metadata
|
|
|
ANI160
|
CABA |
Copper Age |
Bulgaria |
M |
-4685 |
-4499 |
H1ag |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3310T (MT-ND1): Diabetes / HCM (Reported)
|
ANI163
|
CABA |
Copper Age |
Bulgaria |
F |
-4711 |
-4542 |
H7a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
DA145
|
IAST |
Iron Age |
Russia |
M |
0 |
100 |
U2e1h |
bam
|
26.93
|
|
FASTA
Metadata
|
|
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
|
I5469
|
BABI |
Bronze Age |
Great Britain |
F |
-1642 |
-1503 |
H5'36 |
bam
|
3.25
|
|
FASTA
Metadata
|
|
|
RISE154
|
UNC |
Bronze Age |
Poland |
F |
-1925 |
-1765 |
K1a4a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I2860
|
BABI |
Bronze Age |
Great Britain |
M |
-969 |
-815 |
H5a1 |
bam
|
1659.05
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4336C (MT-TQ): ADPD / Hearing Loss & Migraine / autism spectrum / intellectual disability (Unclear)
|
I1530
|
BBC |
Copper Age |
Germany |
M |
-2458 |
-2140 |
H3ao |
<NA>
|
<NA>
|
|
Metadata
|
|
|
LICOL1
|
LONG |
Middle Ages |
Italy |
U |
570 |
800 |
None |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I4556
|
IAIB |
Iron Age |
Spain |
F |
-700 |
-500 |
K1a12a |
bam
|
39.62
|
|
Metadata
|
|
|
I2859
|
BABI |
Bronze Age |
Great Britain |
M |
-910 |
-809 |
K1a2c |
bam
|
1521.11
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
RISE480
|
BAHu |
Bronze Age |
Hungary |
F |
-1700 |
-1500 |
U5a2a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
Villabruna
|
HGS |
Epigravettian |
Italy |
M |
-12230 |
-11830 |
U5b2b |
bam
|
14.80
|
|
FASTA
Metadata
|
|
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
12634G (MT-ND5): Thyroid Cancer Cell Line (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16270T (MT-CR): Melanoma patients (Reported)
|
DA146
|
IACA |
Iron Age |
Russia |
F |
300 |
1400 |
HV2a1 |
bam
|
44.95
|
|
FASTA
Metadata
|
|
-
16217C (MT-CR): Endometriosis (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
|
I3130
|
BABI |
Bronze Age |
Great Britain |
F |
-977 |
-829 |
U5a1c |
bam
|
970.75
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
7080C (MT-CO1): Prostate Cancer (Reported)
|
I2364
|
BBC |
Copper Age |
Hungary |
M |
-2468 |
-2063 |
U5a2b |
bam
|
119.70
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I3499
|
CABA |
Copper Age |
Croatia |
M |
-2884 |
-2666 |
T2e |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I3528
|
BBC |
Copper Age |
Hungary |
M |
-2559 |
-2301 |
HV4a1+16291 |
bam
|
219.38
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0634
|
NEBA |
Neolithic |
Serbia |
M |
-4710 |
-4504 |
K1a4 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I2792
|
CABA |
Copper Age |
Croatia |
M |
-2872 |
-2582 |
T2c2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
3394C (MT-ND1): LHON / Diabetes / CPTdeficiency / high altitude adaptation (Reported / Population-dependent)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
-
6261A (MT-CO1): Prostate Cancer / LHON (Reported)
|
I4175
|
CABA |
Copper Age |
Croatia |
F |
-3000 |
-2700 |
U4a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
3316A (MT-ND1): Diabetes / LHON / PEO (Unclear)
-
499A (MT-CR): Endometriosis (Reported)
|
I3326
|
IAIB |
Iron Age |
Spain |
M |
-250 |
-200 |
J1c |
bam
|
1.04
|
|
Metadata
|
|
|
I2656
|
BABI |
Bronze Age |
Great Britain |
M |
-1278 |
-979 |
H2a2a2 |
bam
|
115.72
|
|
FASTA
Metadata
|
|
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
BerryAuBac1
|
HGW |
Mesolithic |
France |
M |
-5370 |
-5220 |
U5b1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I1875
|
HGS |
Mesolithic |
Croatia |
F |
-7308 |
-7027 |
U5b2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
12634G (MT-ND5): Thyroid Cancer Cell Line (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16270T (MT-CR): Melanoma patients (Reported)
|
DA160
|
IACA |
Iron Age |
Russia |
F |
300 |
1400 |
U4d3 |
bam
|
247.76
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
14577C (MT-ND6): MIDM (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I5376
|
BBC |
Bronze Age |
Great Britain |
F |
-2454 |
-2141 |
H6a1b |
bam
|
19.19
|
|
FASTA
Metadata
|
|
|
I2653
|
BABI |
Bronze Age |
Great Britain |
M |
-1500 |
-1300 |
H2a1a |
bam
|
102.47
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2105
|
YAM |
Bronze Age |
Ukraine |
F |
-3300 |
-2700 |
T1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
DA161
|
IACA |
Iron Age |
Russia |
M |
300 |
1400 |
X2f |
bam
|
33.98
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
|
RISE546
|
YAM |
Bronze Age |
Russia |
M |
-3000 |
-2400 |
U5a1d2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I2654
|
BABI |
Bronze Age |
Great Britain |
F |
-1500 |
-1300 |
U5b3 |
bam
|
76.42
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I3324
|
IAIB |
Iron Age |
Spain |
M |
-360 |
-193 |
H1 |
bam
|
577.00
|
|
Metadata
|
|
|
RISE552
|
YAM |
Bronze Age |
Russia |
M |
-2849 |
-2143 |
T2a1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
14687G (MT-TE): Mito myopathy w respiratory failure / intellectual disability (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I0261
|
BBC |
Copper Age |
Spain |
M |
-2850 |
-2250 |
U5b1i |
bam
|
273.49
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I0823
|
BBC |
Copper Age |
Spain |
F |
-2850 |
-2250 |
H1 |
bam
|
88.67
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I3141
|
YAM |
Bronze Age |
Ukraine |
F |
-3300 |
-2700 |
H15b1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
6253C (MT-CO1): Prostate Cancer / enriched in POAG cohort (Reported)
|
I2655
|
BABI |
Bronze Age |
Great Britain |
M |
-1441 |
-1272 |
H6a1b2 |
bam
|
1123.99
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0444
|
YAM |
Bronze Age |
Russia |
M |
-3335 |
-2882 |
H6a1b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I1917
|
YAM |
Bronze Age |
Ukraine |
F |
-3095 |
-2915 |
R0a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
827G (MT-RNR1): DEAF (Conflicting reports)
|
I2660
|
NEBI |
Neolithic |
Great Britain |
M |
-3513 |
-3352 |
U5a2+16194 |
bam
|
110.18
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I2691
|
NEBI |
Neolithic |
Great Britain |
M |
-3700 |
-3639 |
J1c1 |
bam
|
479.83
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3394C (MT-ND1): LHON / Diabetes / CPTdeficiency / high altitude adaptation (Reported / Population-dependent)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I1298
|
NEBA |
Neolithic |
Bulgaria |
F |
-6032 |
-5837 |
K1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
DA162
|
IACA |
Iron Age |
Russia |
M |
300 |
1400 |
H13a2c |
bam
|
772.73
|
|
FASTA
Metadata
|
|
|
Denisova3
|
HGE |
Upper Paleolithic |
Russia |
F |
-48000 |
-30000 |
L |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12311C (MT-TL2): CPEO (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
12477C (MT-ND5): possible HCM susceptibility (Reported)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
13276G (MT-ND5): MIDD+retinopathy (Conflicting reports)
-
13528G (MT-ND5): LHON-like / LHON / MELAS (Reported)
-
14693G (MT-TE): MELAS / LHON / DEAF / hypertension helper (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16081G (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3277A (MT-TL1): Poss. hypertension factor (Reported)
-
3290C (MT-TL1): Poss. hypertension factor (Reported)
-
3421A (MT-ND1): MIDD (Reported)
-
3496T (MT-ND1): LHON (Reported / Secondary)
-
4456T (MT-TM): Poss. hypertension factor (Reported)
-
4659A (MT-ND2): possible PD risk factor / LHON (Reported)
-
5821A (MT-TC): DEAF helper mut. (Reported)
-
6150A (MT-CO1): Prostate Cancer / enriched in POAG cohort (Reported)
-
7868T (MT-CO2): LHON (Possibly synergistic)
-
827G (MT-RNR1): DEAF (Conflicting reports)
-
8021G (MT-CO2): Asthenozoospermia (Reported)
-
9966A (MT-CO3): LHON possible helper variant (Reported)
|
LICOL13
|
LONG |
Middle Ages |
Italy |
U |
570 |
800 |
None |
<NA>
|
<NA>
|
|
Metadata
|
|
|
KZ1
|
LDN |
Neolithic |
Poland |
F |
-4332 |
-4066 |
U5b2a1a |
fasta
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0443
|
YAM |
Bronze Age |
Russia |
M |
-3300 |
-2700 |
W3a1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15784C (MT-CYB): POAG - potential for association (Reported)
-
15951G (MT-TT): LHON / LHON modulator (Conflicting reports)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I2650
|
NEBI |
Neolithic |
Great Britain |
M |
-3638 |
-3380 |
T2c1d1 |
bam
|
205.35
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
-
6261A (MT-CO1): Prostate Cancer / LHON (Reported)
|
I1541
|
CWC |
Neolithic |
Germany |
M |
-2500 |
-2050 |
U2e1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
|
I12410
|
IAIB |
Iron Age |
Spain |
M |
-515 |
-375 |
H |
bam
|
648.40
|
|
Metadata
|
|
|
KZ2
|
LDN |
Neolithic |
Poland |
F |
-4331 |
-4057 |
K1c |
fasta
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
KZ4
|
LDN |
Neolithic |
Poland |
F |
-4329 |
-3997 |
K1a4 |
fasta
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
DA164
|
IACA |
Iron Age |
Russia |
F |
300 |
1400 |
H5 |
bam
|
229.50
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5549A (MT-TW): DEMCHO (Reported)
|
I2176
|
BABA |
Bronze Age |
Bulgaria |
M |
-3338 |
-3025 |
U1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
|
I0257
|
BBC |
Copper Age |
Spain |
M |
-2572 |
-2348 |
H1ax |
bam
|
319.79
|
|
FASTA
Metadata
|
|
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
I0360
|
SRU |
Bronze Age |
Russia |
M |
-1850 |
-1200 |
U5a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
3398C (MT-ND1): DMDF+HCM / GDM / possibly LVNC cardiomyopathy-associated (Reported)
-
9966A (MT-CO3): LHON possible helper variant (Reported)
|
I0826
|
BBC |
Copper Age |
Spain |
M |
-2834 |
-2482 |
H1t |
bam
|
107.57
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2630
|
NEBI |
Neolithic |
Great Britain |
M |
-2580 |
-2463 |
K1a4 |
bam
|
158.66
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
6663G (MT-CO1): Prostate Cancer (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
SCY300
|
SCU |
Iron Age |
Moldova |
F |
-400 |
-200 |
H5b |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0175
|
LDN |
Neolithic |
Hungary |
U |
-4900 |
-4500 |
N1a1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
3336C (MT-ND1): Carotid atherosclerosis risk (Reported)
-
669C (MT-RNR1): DEAF (Reported)
|
I0166
|
LDN |
Neolithic |
Germany |
U |
-5500 |
-4775 |
V1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I2405
|
GAC |
Bronze Age |
Poland |
M |
-3335 |
-3020 |
W5 |
fasta
|
17.05
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I2932
|
NEBI |
Neolithic |
Great Britain |
M |
-2570 |
-2347 |
H5 |
bam
|
780.40
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
SCY305
|
SCU |
Iron Age |
Moldova |
U |
-400 |
-200 |
U5a2b |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
SCY308
|
SCU |
Iron Age |
Moldova |
U |
-400 |
-200 |
F1d |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
-
5628C (MT-TA): CPEO / DEAF enhancer / gout (Reported)
-
6962A (MT-CO1): Possible helper variant for 15927A (Reported)
|
I0165
|
LDN |
Neolithic |
Germany |
U |
-4625 |
-4250 |
U5b1b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I2933
|
NEBI |
Neolithic |
Great Britain |
M |
-3010 |
-2885 |
J1c2 |
bam
|
432.32
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I12877
|
IAIB |
Iron Age |
Spain |
M |
-515 |
-375 |
J1c1 |
bam
|
41.54
|
|
Metadata
|
|
|
I0556
|
BAC |
Neolithic |
Germany |
U |
-3950 |
-3400 |
U8a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
|
I6582
|
BBC |
Copper Age |
Poland |
F |
-2343 |
-2057 |
U5a2b |
bam
|
339.39
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I0102
|
LBK |
Neolithic |
Germany |
U |
-5030 |
-4948 |
N1a1a1a3 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
3336C (MT-ND1): Carotid atherosclerosis risk (Reported)
-
669C (MT-RNR1): DEAF (Reported)
|
I0796
|
LBK |
Neolithic |
Germany |
U |
-5500 |
-4775 |
H |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
SCY311
|
SCU |
Iron Age |
Moldova |
F |
-400 |
-200 |
T2b |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I0799
|
SCG |
Neolithic |
Germany |
U |
-4100 |
-3950 |
H1e |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I2418
|
BBC |
Bronze Age |
Great Britain |
F |
-2455 |
-2200 |
K1a4a1 |
bam
|
752.01
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I2934
|
NEBI |
Neolithic |
Great Britain |
F |
-3338 |
-3022 |
U5a2c3 |
bam
|
452.01
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0820
|
LBK |
Neolithic |
Germany |
U |
-5298 |
-5247 |
W1c'i |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I2935
|
NEBI |
Neolithic |
Great Britain |
M |
-3335 |
-3011 |
U8b1b |
bam
|
610.26
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
SCY334
|
SCU |
Iron Age |
Moldova |
U |
-400 |
-200 |
H5b |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
228A (MT-CR): Low VO2max response (Reported)
|
DA179
|
MAST |
Middle Ages |
Kazakhstan |
M |
1200 |
1400 |
D4 |
bam
|
317.38
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
14668T (MT-ND6): Depressive Disorder associated (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4440A (MT-TM): Mitochondrial myopathy (Reported)
-
4454C (MT-TM): Possible contributor to mito dysfunction / hypertension (Reported)
-
4883T (MT-ND2): Glaucoma (Conflicting reports)
-
489C (MT-CR): Low VO2max response (Reported)
-
8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
|
I3085
|
NEBI |
Neolithic |
Great Britain |
F |
-3338 |
-3026 |
K1a+195 |
bam
|
607.89
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
SCY002
|
SCU |
Iron Age |
Ukraine |
U |
-400 |
-400 |
J1c2 |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
DA189
|
MAST |
Middle Ages |
Russia |
M |
700 |
1000 |
J1b4 |
bam
|
167.46
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
295T (MT-CR): Low VO2max response (Reported)
-
3290C (MT-TL1): Poss. hypertension factor (Reported)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I0024
|
LBK |
Neolithic |
Germany |
U |
-5500 |
-4800 |
W1c'i |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I12640
|
IAIB |
Iron Age |
Spain |
M |
-696 |
-540 |
H1t |
bam
|
16.57
|
|
Metadata
|
|
|
I2977
|
NEBI |
Neolithic |
Great Britain |
M |
-3008 |
-2763 |
H1 |
bam
|
619.04
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I6581
|
BBC |
Copper Age |
Poland |
M |
-2455 |
-2145 |
H6a1a |
bam
|
186.09
|
|
FASTA
Metadata
|
|
-
11253C (MT-ND4): LHON PD (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
DA191
|
SCHu |
Iron Age |
Hungary |
F |
-536 |
-526 |
H2a2 |
bam
|
3.33
|
|
FASTA
Metadata
|
|
|
I2629
|
NEBI |
Neolithic |
Great Britain |
M |
-3180 |
-2780 |
J1c1b |
bam
|
1.82
|
|
FASTA
Metadata
|
|
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
|
SCY006
|
SCU |
Iron Age |
Ukraine |
F |
-700 |
-700 |
D4j2 |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11696A (MT-ND4): LHON / LDYT / DEAF / hypertension helper mut. (Reported - possibly synergistic)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
14668T (MT-ND6): Depressive Disorder associated (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
4883T (MT-ND2): Glaucoma (Conflicting reports)
-
489C (MT-CR): Low VO2max response (Reported)
-
5178A (MT-ND2): Longevity / Extraversion / diabetes / AMS protection / blood iron metabolism / correlation with myocardial infarction / atherosclerosis (Reported)
-
8414T (MT-ATP8): Increased risk of T2DM and high altitude polycythemia (HAPC) in haplogroup D4 / Longevity (Reported)
|
I2978
|
NEBI |
Neolithic |
Great Britain |
M |
-3335 |
-3023 |
K1b1a1 |
bam
|
637.85
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13967T (MT-ND5): Possible LHON factor (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I2441
|
GAC |
Bronze Age |
Poland |
M |
-3400 |
-2800 |
K1b1a1 |
fasta
|
244.58
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13967T (MT-ND5): Possible LHON factor (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I12642
|
IAIB |
Iron Age |
Spain |
F |
-731 |
-399 |
H |
bam
|
168.00
|
|
Metadata
|
|
|
SCY011
|
SCU |
Iron Age |
Ukraine |
F |
-400 |
-400 |
A |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
-
8794T (MT-ATP6): Exercise Endurance / Coronary Atherosclerosis risk (Reported)
|
I2565
|
BBC |
Bronze Age |
Great Britain |
M |
-2457 |
-2147 |
W1+119 |
bam
|
44.65
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I4253
|
BBC |
Copper Age |
Poland |
M |
-2456 |
-2207 |
U5a2c |
bam
|
1073.95
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2631
|
NEBI |
Neolithic |
Great Britain |
M |
-3097 |
-2906 |
H5 |
bam
|
887.83
|
|
FASTA
Metadata
|
|
|
I3133
|
NEBI |
Neolithic |
Great Britain |
M |
-3631 |
-3377 |
K1a+195 |
bam
|
659.83
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
7158G (MT-CO1): Prostate Cancer (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
SCY009
|
SCU |
Iron Age |
Ukraine |
M |
-700 |
-700 |
J2b1a6 |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
15662G (MT-CYB): Complex mitochondriopathy-associated (Reported)
-
15812A (MT-CYB): LHON (Reported / Secondary)
-
295T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
-
9016G (MT-ATP6): LHON (Reported)
|
I3134
|
NEBI |
Neolithic |
Great Britain |
M |
-3633 |
-3377 |
T2f4 |
bam
|
482.12
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I3322
|
IAIB |
Iron Age |
Spain |
F |
-600 |
-500 |
H1t |
bam
|
632.00
|
|
Metadata
|
|
|
DA195
|
SCHu |
Iron Age |
Hungary |
F |
-756 |
-727 |
H+16311 |
bam
|
130.03
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I6774
|
BBC |
Bronze Age |
Great Britain |
M |
-2287 |
-2044 |
H4a1a1a |
bam
|
93.45
|
|
FASTA
Metadata
|
|
-
10044G (MT-TG): SIDS (Unclear)
-
14582G (MT-ND6): LHON synergistic combo 14258A + 14582G (Reported: individually neutral variants causing LHON in combination)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I12561
|
IAIB |
Iron Age |
Spain |
M |
-700 |
-500 |
H1 |
bam
|
3.15
|
|
Metadata
|
|
|
I2459
|
BBC |
Bronze Age |
Great Britain |
F |
-2455 |
-2150 |
T2a1a |
bam
|
340.09
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
14687G (MT-TE): Mito myopathy w respiratory failure / intellectual disability (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
SCY005
|
SCU |
Iron Age |
Ukraine |
F |
-300 |
-200 |
H |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
7697A (MT-CO2): Possible HCM susceptibility / high altitude adaptation (Reported)
|
I3135
|
NEBI |
Neolithic |
Great Britain |
M |
-3640 |
-3383 |
U5b2a |
bam
|
825.83
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
Sam1
|
LBK |
Neolithic |
Poland |
F |
-5500 |
-4800 |
N1a1a1a |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
3336C (MT-ND1): Carotid atherosclerosis risk (Reported)
-
669C (MT-RNR1): DEAF (Reported)
|
I3137
|
NEBI |
Neolithic |
Great Britain |
M |
-3800 |
-3200 |
HV0+195 |
bam
|
81.92
|
|
FASTA
Metadata
|
|
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
KM1
|
LDN |
Neolithic |
Poland |
F |
-4700 |
-3800 |
U5b1b |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I3138
|
NEBI |
Neolithic |
Great Britain |
F |
-3263 |
-2923 |
K1a4a1 |
bam
|
797.42
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I5757
|
BBC |
Copper Age |
Switzerland |
M |
-2469 |
-1984 |
H3af |
bam
|
209.07
|
|
FASTA
Metadata
|
|
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
|
I3214
|
NEIB |
Neolithic |
Spain |
M |
-3400 |
-2500 |
V3 |
bam
|
11.20
|
|
Metadata
|
|
|
KZ6
|
LDN |
Neolithic |
Poland |
F |
-4400 |
-4000 |
N1a1a1a3 |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
3336C (MT-ND1): Carotid atherosclerosis risk (Reported)
-
669C (MT-RNR1): DEAF (Reported)
|
I3041
|
NEBI |
Neolithic |
Great Britain |
M |
-3942 |
-3037 |
K1a3a |
bam
|
445.11
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I8210
|
CLIB |
Classical Age |
Spain |
M |
-500 |
-350 |
U5b3 |
bam
|
7.00
|
|
Metadata
|
|
|
I3948
|
NEBA |
Neolithic |
Croatia |
M |
-6005 |
-5814 |
N1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
3336C (MT-ND1): Carotid atherosclerosis risk (Reported)
-
669C (MT-RNR1): DEAF (Reported)
|
I7643
|
NEIB |
Neolithic |
Spain |
M |
-3960 |
-3710 |
K1a1b1 |
bam
|
27.20
|
|
Metadata
|
|
|
I5370
|
NEBI |
Neolithic |
Great Britain |
F |
-4000 |
-3300 |
K1a+195 |
bam
|
19.19
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
R18_1
|
LDN |
Neolithic |
Poland |
F |
-5364 |
-5398 |
K2a |
reconstructed
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
DA198
|
SCHu |
Iron Age |
Hungary |
M |
-508 |
-498 |
H7a1 |
bam
|
74.71
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I4872
|
HGS |
Mesolithic |
Serbia |
F |
-7100 |
-5900 |
U5a1c |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I2634
|
NEBI |
Neolithic |
Great Britain |
M |
-3703 |
-3534 |
U2+152 |
bam
|
179.11
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3394C (MT-ND1): LHON / Diabetes / CPTdeficiency / high altitude adaptation (Reported / Population-dependent)
|
PCA0001
|
MAPl |
Middle Ages |
Poland |
M |
80 |
260 |
W |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I4229
|
BBC |
Copper Age |
Portugal |
M |
-2336 |
-2063 |
U5a2+16362 |
bam
|
346.16
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2633
|
NEBI |
Neolithic |
Great Britain |
F |
-3765 |
-3641 |
T2e1 |
bam
|
432.82
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I7554
|
NEBI |
Neolithic |
Great Britain |
M |
-3366 |
-3103 |
J1c9 |
bam
|
137.01
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I1775
|
BABI |
Bronze Age |
Great Britain |
M |
-1730 |
-1532 |
I3 |
bam
|
693.67
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2574
|
BABI |
Bronze Age |
Great Britain |
F |
-1414 |
-1227 |
U5a1a2b |
bam
|
985.86
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
PCA0003
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
H5a1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I6466
|
BBC |
Copper Age |
Portugal |
M |
-2700 |
-2300 |
K1b1a1 |
bam
|
30.22
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13967T (MT-ND5): Possible LHON factor (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I5358
|
NEBI |
Neolithic |
Great Britain |
F |
-3080 |
-2904 |
K1a1 |
bam
|
82.21
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
114T (MT-CR): BD-associated (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
PCA0004
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
U3a1a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12300A (MT-TL2): 3243 suppressor mutant (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
14258A (MT-ND6): LHON synergistic combo 10680A + 12033G + 14258A also combo 14258A + 14582G (Reported: individually neutral variants causing LHON in combination)
-
15024A (MT-CYB): Possible DEAF modifier (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
15153A (MT-CYB): Suspected mito disease (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
3460A (MT-ND1): LHON (Cfrm)
|
DA199
|
MAHu |
Middle Ages |
Hungary |
F |
1224 |
1264 |
H1ba |
bam
|
68.65
|
|
FASTA
Metadata
|
|
-
16270T (MT-CR): Melanoma patients (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
I8341
|
CLIB |
Classical Age |
Spain |
M |
-500 |
-350 |
H1 |
bam
|
110.00
|
|
Metadata
|
|
|
PCA0006
|
MAPl |
Middle Ages |
Poland |
F |
80 |
120 |
U5a1d1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
14459A (MT-ND6): LDYT / Leigh Disease / dystonia / carotid atherosclerosis risk (Cfrm)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
4320T (MT-TI): Mitochondrial Encephalocardiomyopathy (Reported)
-
4327C (MT-TI): Ataxia+ / with RRF and COX deficiency (Reported)
-
5532A (MT-TW): Gastrointestinal Syndrome (Reported)
|
PCA0015
|
MAPl |
Middle Ages |
Poland |
M |
80 |
260 |
H1f1a |
<NA>
|
<NA>
|
|
Metadata
|
|
|
PCA0007
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
W1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
3635A (MT-ND1): LHON (Cfrm)
-
4450A (MT-TM): Myopathy / MELAS / Leigh Syndrome (Cfrm)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I5359
|
NEBI |
Neolithic |
Great Britain |
M |
-3800 |
-3600 |
H5 |
bam
|
100.37
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I5367
|
BBC |
Bronze Age |
Great Britain |
F |
-2467 |
-2232 |
V10 |
bam
|
374.63
|
|
FASTA
Metadata
|
|
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
DA201
|
IAKa |
Iron Age |
Kazakhstan |
F |
-171 |
-88 |
C4a1a+195 |
bam
|
111.11
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3552A (MT-ND1): Resistance to high altitude pulmonary edema (HAPE) (Reported /hg C marker)
-
489C (MT-CR): Low VO2max response (Reported)
|
I4882
|
HGS |
Mesolithic |
Serbia |
M |
-6200 |
-5900 |
U4b1b1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13528G (MT-ND5): LHON-like / LHON / MELAS (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I8344
|
CLIB |
Classical Age |
Spain |
M |
-500 |
-400 |
H3 |
bam
|
178.00
|
|
Metadata
|
|
|
I7250
|
BBC |
Copper Age |
Czech Republic |
F |
-2500 |
-2200 |
R1a1a |
bam
|
43.66
|
|
FASTA
Metadata
|
|
-
1391C (MT-RNR1): found in 1 HCM patient (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
PCA0026
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
T2b16 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
1310T (MT-RNR1): DEAF-associated (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I3875
|
BBC |
Copper Age |
France |
M |
-2133 |
-1946 |
H1e |
bam
|
423.99
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I4607
|
HGS |
Mesolithic |
Romania |
M |
-7340 |
-6640 |
U5a2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
8481T (MT-ATP8): Tetralogy of Fallot patient (Reported)
|
I4067
|
BBC |
Copper Age |
The Netherlands |
F |
-1946 |
-1690 |
R1b1 |
bam
|
135.49
|
|
FASTA
Metadata
|
|
-
1095C (MT-RNR1): SNHL (Unclear)
-
1391C (MT-RNR1): found in 1 HCM patient (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I0462
|
BBC |
Copper Age |
Spain |
F |
-2566 |
-2345 |
K1a+195 |
bam
|
240.45
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I7279
|
CWC |
Neolithic |
Czech Republic |
M |
-2900 |
-2200 |
H7d |
bam
|
118.87
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
DA202
|
IAST |
Iron Age |
Kazakhstan |
F |
-733 |
-690 |
U5a1 |
bam
|
20.96
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I7275
|
BBC |
Copper Age |
Czech Republic |
M |
-2500 |
-2200 |
U5b2c |
bam
|
309.84
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
I5042
|
EBACz |
Bronze Age |
Czech Republic |
M |
-2300 |
-1900 |
I4a |
bam
|
168.65
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
8519A (MT-ATP8): Susceptibility to bullous pemphigoid (Reported)
|
I6476
|
BBC |
Copper Age |
Czech Republic |
F |
-2500 |
-1900 |
U5a1b1 |
bam
|
596.50
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I8206
|
CLIB |
Classical Age |
Spain |
M |
-300 |
-100 |
H7a1 |
bam
|
43.40
|
|
Metadata
|
|
|
PCA0030
|
MAPl |
Middle Ages |
Poland |
F |
110 |
160 |
H2a2b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I5043
|
EBACz |
Bronze Age |
Czech Republic |
M |
-2300 |
-1900 |
U4c1a |
bam
|
672.69
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I5665
|
BBC |
Copper Age |
Spain |
M |
-2280 |
-1984 |
K1a24a |
bam
|
480.15
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I4946
|
BBC |
Copper Age |
Czech Republic |
F |
-2296 |
-2146 |
I4a |
bam
|
397.00
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
8519A (MT-ATP8): Susceptibility to bullous pemphigoid (Reported)
|
PCA0031
|
MAPl |
Middle Ages |
Poland |
F |
10 |
375 |
K2a |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I7195
|
UNC |
Bronze Age |
Czech Republic |
F |
-2200 |
-1700 |
H3v+16093 |
bam
|
303.35
|
|
FASTA
Metadata
|
|
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
|
I4655
|
HGS |
Mesolithic |
Romania |
M |
-7060 |
-6570 |
K1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I4947
|
BBC |
Copper Age |
Czech Republic |
M |
-2500 |
-2000 |
H17a |
bam
|
602.04
|
|
FASTA
Metadata
|
|
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
DA203
|
MAST |
Middle Ages |
Kazakhstan |
M |
950 |
1250 |
G2a2 |
bam
|
139.30
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
4833G (MT-ND2): Diabetes helper mutation AD / PD (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
PCA0036
|
MAPl |
Middle Ages |
Poland |
M |
80 |
260 |
U5b1d1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
869T (MT-RNR1): found in 1 HCM patient (Reported)
|
I4247
|
BBC |
Copper Age |
Spain |
F |
-2464 |
-2210 |
T2b3 |
bam
|
87.29
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I7196
|
UNC |
Bronze Age |
Czech Republic |
M |
-2200 |
-1700 |
K1a+195 |
bam
|
294.60
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I7197
|
UNC |
Bronze Age |
Czech Republic |
M |
-2200 |
-1700 |
X2b6 |
bam
|
323.64
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
15927A (MT-TT): LHON / Multiple Sclerosis / DEAF1555 increased penetrance / CHD (Reported)
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
8393T (MT-ATP8): Reversible brain pseudoatrophy (Reported)
|
I8202
|
CLIB |
Classical Age |
Spain |
M |
100 |
300 |
K2b1 |
bam
|
77.90
|
|
Metadata
|
|
|
PCA0041
|
MAPl |
Middle Ages |
Poland |
M |
80 |
260 |
N |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I7199
|
UNC |
Bronze Age |
Czech Republic |
M |
-2200 |
-1700 |
J1c3a |
bam
|
297.14
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I4889
|
BBC |
Copper Age |
Czech Republic |
M |
-2281 |
-2062 |
U4a2 |
bam
|
127.62
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I7201
|
UNC |
Bronze Age |
Czech Republic |
F |
-2200 |
-1700 |
U5a1a2b |
bam
|
168.25
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
PCA0044
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
H5a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
2835T (MT-RNR2): Rett Syndrome (Reported)
-
4336C (MT-TQ): ADPD / Hearing Loss & Migraine / autism spectrum / intellectual disability (Unclear)
|
I4884
|
EBACz |
Bronze Age |
Czech Republic |
M |
-1882 |
-1745 |
H4a1a1a |
bam
|
101.12
|
|
FASTA
Metadata
|
|
-
10044G (MT-TG): SIDS (Unclear)
-
14582G (MT-ND6): LHON synergistic combo 14258A + 14582G (Reported: individually neutral variants causing LHON in combination)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
PCA0045
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
U5b1d1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I5237
|
HGS |
Mesolithic |
Serbia |
M |
-9500 |
-6200 |
U5a2a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
|
I5236
|
HGS |
Mesolithic |
Serbia |
M |
-8290 |
-7825 |
U5a2d |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I5411
|
HGS |
Mesolithic |
Romania |
M |
-7000 |
-6300 |
U5a1c1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I5239
|
HGS |
Mesolithic |
Serbia |
F |
-8535 |
-8230 |
U5a2d |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I7211
|
BBC |
Copper Age |
Czech Republic |
F |
-2500 |
-2200 |
U5b3 |
bam
|
319.75
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16270T (MT-CR): Melanoma patients (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
DA205
|
MAST |
Middle Ages |
Kazakhstan |
F |
950 |
1250 |
J1c |
bam
|
206.67
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
15924G (MT-TT): LIMM (Reported)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
PCA0046
|
MAPl |
Middle Ages |
Poland |
M |
110 |
160 |
U8a1a1b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
|
I4892
|
EBACz |
Bronze Age |
Czech Republic |
F |
-1881 |
-1701 |
T1a1 |
bam
|
152.98
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I4893
|
NECz |
Neolithic |
Czech Republic |
M |
-4449 |
-4348 |
U5b1b1 |
bam
|
205.24
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I8338
|
CLIB |
Classical Age |
Spain |
F |
100 |
200 |
HV0+195 |
bam
|
107.00
|
|
Metadata
|
|
|
PCA0047
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
H5a1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
4336C (MT-TQ): ADPD / Hearing Loss & Migraine / autism spectrum / intellectual disability (Unclear)
|
I7286
|
BBC |
Copper Age |
Czech Republic |
M |
-2500 |
-2200 |
I4a |
bam
|
223.85
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
15043A (MT-CYB): MDD-associated (Reported)
-
15924G (MT-TT): LIMM (Reported)
-
16129A (MT-CR): Cyclic Vomiting Syndrome with Migraine (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
6480A (MT-CO1): Prostate Cancer / enriched in POAG cohort (Reported)
-
8519A (MT-ATP8): Susceptibility to bullous pemphigoid (Reported)
|
I4894
|
NECz |
Neolithic |
Czech Republic |
F |
-4488 |
-4368 |
U8b1b1 |
bam
|
202.73
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I4303
|
MLN |
Neolithic |
France |
M |
-4778 |
-4586 |
H3 |
bam
|
396.49
|
|
FASTA
Metadata
|
|
|
I8474
|
CLIB |
Classical Age |
Spain |
F |
100 |
200 |
U5a1a2b |
bam
|
23.40
|
|
Metadata
|
|
|
Sarretudvari-Hizofold/9/anc11
|
MAHu |
Middle Ages |
Hungary |
M |
900 |
970 |
T2b |
bam
|
25.00
|
|
Metadata
|
|
|
I7212
|
BBC |
Copper Age |
Czech Republic |
M |
-2500 |
-2200 |
K1b1a1+199 |
bam
|
265.78
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13967T (MT-ND5): Possible LHON factor (Reported)
-
15257A (MT-CYB): LHON (Conflicting reports)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
PCA0049
|
MAPl |
Middle Ages |
Poland |
F |
110 |
160 |
H1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
I4304
|
MLN |
Neolithic |
France |
M |
-4787 |
-4589 |
T2c1d+152 |
bam
|
456.91
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
-
6261A (MT-CO1): Prostate Cancer / LHON (Reported)
|
I6480
|
BBC |
Copper Age |
Czech Republic |
M |
-2500 |
-1900 |
U4a2 |
bam
|
153.39
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I7040
|
BAHu |
Bronze Age |
Hungary |
F |
-2500 |
-2200 |
K1a4b |
bam
|
522.38
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I1381
|
BBC |
Copper Age |
France |
M |
-2400 |
-1900 |
H |
bam
|
599.16
|
|
FASTA
Metadata
|
|
|
PCA0051
|
MAPl |
Middle Ages |
Poland |
F |
110 |
160 |
K2a |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I7043
|
BAHu |
Bronze Age |
Hungary |
M |
-2500 |
-2200 |
H1b1 |
bam
|
455.99
|
|
FASTA
Metadata
|
|
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3796G (MT-ND1): Adult-Onset Dystonia (Reported)
-
6267A (MT-CO1): Prostate Cancer (Reported)
|
DA207
|
MEST |
Modern Era |
Kazakhstan |
M |
1650 |
1850 |
H2a |
bam
|
4.04
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I7041
|
BAHu |
Bronze Age |
Hungary |
M |
-2500 |
-2200 |
H1b1 |
bam
|
458.69
|
|
FASTA
Metadata
|
|
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
3796G (MT-ND1): Adult-Onset Dystonia (Reported)
-
6267A (MT-CO1): Prostate Cancer (Reported)
|
I4070
|
BANl |
Bronze Age |
The Netherlands |
M |
-1880 |
-1657 |
U5a1b1a |
bam
|
138.93
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
PCA0054
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
U3a1a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16390A (MT-CR): POAG - potential for association (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
6285A (MT-CO1): Prostate Cancer (Reported)
-
8328A (MT-TK): Mito Encephalopathy / EXIT with myopathy and ptosis (Reported)
|
I5409
|
HGS |
Mesolithic |
Serbia |
F |
-9500 |
-6200 |
U5a1c |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
|
I5436
|
HGS |
Mesolithic |
Romania |
F |
-7451 |
-6698 |
U5a2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
PCA0056
|
MAPl |
Middle Ages |
Poland |
F |
80 |
260 |
T2b6a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
15928A (MT-TT): Multiple Sclerosis / idiopathic repeat miscarriage / AD protection (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
4917G (MT-ND2): LHON / Insulin Resistance / AMD / NRTI-PN (Reported)
|
I4071
|
BANl |
Bronze Age |
The Netherlands |
F |
-1883 |
-1664 |
H6a1a |
bam
|
259.20
|
|
FASTA
Metadata
|
|
-
11253C (MT-ND4): LHON PD (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I6491
|
CLIB |
Classical Age |
Spain |
M |
200 |
500 |
H4a1a |
bam
|
7.40
|
|
Metadata
|
|
|
DA208
|
MEST |
Modern Era |
Kazakhstan |
M |
1650 |
1850 |
H1 |
bam
|
8.24
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
PCA0057
|
MAPl |
Middle Ages |
Poland |
F |
110 |
160 |
J1c7a |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
4216C (MT-ND1): LHON / Insulin Resistance /possible adaptive high altitude variant / miscarriage (Conflicting reports)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
I6531
|
EBAPl |
Bronze Age |
Poland |
M |
-2286 |
-2038 |
U5b2b1a1 |
bam
|
267.70
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
12634G (MT-ND5): Thyroid Cancer Cell Line (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
15497A (MT-CYB): EXIT / Obesity (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2754
|
CAHu |
Copper Age |
Hungary |
M |
-3337 |
-3024 |
J1c |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I6579
|
EBAPl |
Bronze Age |
Poland |
F |
-2335 |
-2046 |
K1a4a1g |
bam
|
321.42
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
ANI153
|
CABA |
Copper Age |
Bulgaria |
M |
-4551 |
-4374 |
U4 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12063T (MT-ND4): Recurrent pregnancy loss (Reported)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
|
ANI152
|
CABA |
Copper Age |
Bulgaria |
M |
-4683 |
-4406 |
U2 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
3275T (MT-TL1): Metabolic syndrome and polycystic ovary syndrome (Reported)
|
I3589
|
BBC |
Copper Age |
Germany |
M |
-2300 |
-2150 |
U4d1 |
bam
|
561.05
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I3599
|
BBC |
Copper Age |
Germany |
M |
-2300 |
-2150 |
H1e1a |
bam
|
54.63
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
-
8821G (MT-ATP6): Possible LHON helper variant (Reported)
|
I2755
|
CAHu |
Copper Age |
Hungary |
M |
-3600 |
-3000 |
U8b1a1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
Ust_Ishim
|
HGE |
Upper Paleolithic |
Russia |
M |
-45530 |
-40610 |
R* |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
|
I2788
|
CAHu |
Copper Age |
Hungary |
M |
-3910 |
-3650 |
H |
<NA>
|
<NA>
|
|
Metadata
|
|
|
PCA0060
|
MAPl |
Middle Ages |
Poland |
M |
80 |
260 |
U5b1d1 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
I3593
|
BBC |
Copper Age |
Germany |
F |
-2397 |
-2145 |
H1 |
bam
|
236.53
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
DA220
|
IAKa |
Iron Age |
Kazakhstan |
M |
-350 |
-50 |
HV6 |
bam
|
111.75
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I2789
|
CAHu |
Copper Age |
Hungary |
M |
-3800 |
-3600 |
J1c3b |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I8343
|
CLIB |
Classical Age |
Spain |
M |
500 |
600 |
J1c2c2 |
bam
|
171.00
|
|
Metadata
|
|
|
I3866
|
MAIB |
Middle Ages |
Spain |
M |
600 |
700 |
U5a1b1 |
bam
|
107.00
|
|
Metadata
|
|
|
PCA0061
|
MAPl |
Middle Ages |
Poland |
U |
80 |
260 |
H1ak |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
|
I2791
|
CAHu |
Copper Age |
Hungary |
M |
-3658 |
-3384 |
U5a1c1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I7600
|
NEIB |
Neolithic |
Spain |
F |
-4100 |
-2700 |
K1a2a |
bam
|
30.30
|
|
Metadata
|
|
|
I6475
|
BBC |
Copper Age |
Spain |
F |
-2500 |
-2000 |
U5b3 |
bam
|
407.07
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
15909G (MT-TT): Hypertension (Reported)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
|
I2371
|
CAHu |
Copper Age |
Hungary |
M |
-3359 |
-3098 |
U5b3f |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I1553
|
BBC |
Copper Age |
Spain |
F |
-2850 |
-2250 |
pre-H103 |
bam
|
10.62
|
|
FASTA
Metadata
|
|
|
E09613_d
|
BBC |
Copper Age |
Germany |
F |
-2289 |
-2140 |
H1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
DA221
|
IAKa |
Iron Age |
Kazakhstan |
M |
-790 |
-747 |
J1b1a1 |
bam
|
1184.38
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
295T (MT-CR): Low VO2max response (Reported)
-
2158C (MT-RNR2): Reduced risk PD (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
-
5460A (MT-ND2): AD / PD / LHON (Conflicting reports)
|
PCA0063
|
MAPl |
Middle Ages |
Poland |
M |
10 |
375 |
H2a5 |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
|
DA223
|
IAKa |
Iron Age |
Kazakhstan |
M |
-403 |
-374 |
J1c5a |
bam
|
740.55
|
|
FASTA
Metadata
|
|
-
11251G (MT-ND4): Reduced risk of PD (Reported)
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
13708A (MT-ND5): LHON / Increased MS risk / higher freq in PD-ADS (Conflicting reports)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
185A (MT-CR): Low VO2max response (Reported)
-
295T (MT-CR): Low VO2max response (Reported)
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
-
462T (MT-CR): Low VO2max response (Reported)
-
489C (MT-CR): Low VO2max response (Reported)
|
DA224
|
MAST |
Middle Ages |
Kazakhstan |
M |
264 |
273 |
H |
bam
|
6.92
|
|
FASTA
Metadata
|
|
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
I7672
|
MAIB |
Middle Ages |
Spain |
M |
785 |
801 |
T2h |
bam
|
59.80
|
|
Metadata
|
|
|
Gyvakarai1
|
CWC |
Neolithic |
Lithuania |
M |
-2690 |
-2470 |
K1b2a |
fasta
|
7.56
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
5913A (MT-CO1): Prostate Cancer / hypertension (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I1975
|
CAIB |
Copper Age |
Spain |
M |
-3090 |
-2894 |
J1c1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I0262
|
BBC |
Copper Age |
Spain |
F |
-2850 |
-2250 |
U5b3 |
bam
|
275.01
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16270T (MT-CR): Melanoma patients (Reported)
-
228A (MT-CR): Low VO2max response (Reported)
|
I0258
|
BBC |
Copper Age |
Spain |
F |
-2850 |
-2250 |
H1q |
bam
|
110.39
|
|
FASTA
Metadata
|
|
-
3010A (MT-RNR2): Cyclic Vomiting Syndrome with Migraine / high altitude disease risk factor (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
DA227
|
IAKa |
Iron Age |
Kazakhstan |
F |
-350 |
-50 |
U5b2c |
bam
|
11.45
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
|
DA228
|
MAST |
Middle Ages |
Kazakhstan |
M |
550 |
850 |
A15c |
bam
|
24.16
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
4440A (MT-TM): Mitochondrial myopathy (Reported)
-
5650A (MT-TA): Myopathy (Cfrm)
-
663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
|
RISE1
|
CWC |
Neolithic |
Poland |
U |
-2865 |
-2578 |
K1b1a1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I1976
|
CAIB |
Copper Age |
Spain |
M |
-2571 |
-2347 |
H3 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I2478
|
BBC |
Copper Age |
Italy |
M |
-2194 |
-1939 |
K1a2a |
bam
|
251.09
|
|
FASTA
Metadata
|
|
-
10398G (MT-ND3): PD protective factor / longevity / altered cell pH / metabolic syndrome / breast cancer risk / Leigh Syndrome risk / ADHD / cognitive decline / SCA2 age of onset / Fuchs endothelial corneal dystrophy (Reported / lineage L & M marker / also hg IJK)
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
310C (MT-CR): Possible protective factor for normal tension glaucoma (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
I1843
|
CAIB |
Copper Age |
Spain |
F |
-3092 |
-2877 |
U5b1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I1378
|
NEUk |
Neolithic |
Ukraine |
M |
-4519 |
-4343 |
U4b |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
15693C (MT-CYB): Possibly LVNC cardiomyopathy-associated (Reported)
-
195C (MT-CR): BD-associated / melanoma pts (Reported)
-
499A (MT-CR): Endometriosis (Reported)
|
I4936
|
BBC |
Copper Age |
Italy |
F |
-2500 |
-1900 |
K1a |
bam
|
2.97
|
|
FASTA
Metadata
|
|
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
16093C (MT-CR): Cyclic Vomiting Syndrome (Reported)
-
9055A (MT-ATP6): PD protective factor (Reported)
|
DA229
|
IAST |
Iron Age |
Kazakhstan |
M |
-250 |
250 |
A8a1 |
bam
|
3.84
|
|
FASTA
Metadata
|
|
-
12705T (MT-CO1): Possible protective factor for normal tension glaucoma (Reported)
-
146C (MT-CR): Absence of Endometriosis (Reported)
-
4440A (MT-TM): Mitochondrial myopathy (Reported)
-
663G (MT-RNR1): Coronary atherosclerosis risk (Reported)
-
6962A (MT-CO1): Possible helper variant for 15927A (Reported)
|
I0585
|
HGW |
Mesolithic |
Spain |
M |
-5983 |
-5747 |
U5b2c |
bam
|
<NA>
|
|
FASTA
Metadata
|
|
-
11467G (MT-ND4): Altered brain pH / sCJD patients (Reported)
-
12308G (MT-TL2): CPEO / Stroke / CM / Breast & Renal & Prostate Cancer Risk / Altered brain pH /sCJD (Reported)
-
12372A (MT-ND5): Altered brain pH / sCJD patients (Reported)
-
13637G (MT-ND5): Possible LHON factor (Reported)
-
150T (MT-CR): Longevity / Cervical Carcinoma / HPV infection risk (Conflicting reports)
-
16192T (MT-CR): Melanoma patients (Reported)
-
16270T (MT-CR): Melanoma patients (Reported)
|
DA230
|
MAKa |
Middle Ages |
Kazakhstan |
M |
750 |
950 |
F1b1e |
bam
|
837.11
|
|
FASTA
Metadata
|
|
-
16183C (MT-CR): Melanoma patients (Reported)
-
16189C (MT-CR): Diabetes / Cardiomyopathy /cancer risk / mtDNA copy nbr / Metabolic Syndrome / Melanoma patients (Reported)
-
6962A (MT-CO1): Possible helper variant for 15927A (Reported)
|
I1981
|
CAIB |
Copper Age |
Spain |
F |
-3014 |
-2891 |
J1c1 |
<NA>
|
<NA>
|
|
Metadata
|
|
|
RISE145
|
UNC |
Bronze Age |
Poland |
M |
-2188 |
-1958 |
H6a1b |
<NA>
|
<NA>
|
|
Metadata
|
|
|
RISE493
|
BARu |
Bronze Age |
Russia |
M |
-1531 |
-1427 |
C4a1c |
<NA>
|
<NA>
|
|
Metadata
|
|
|
I7673
|
MAIB |
Middle Ages |
Spain |
F |
785 |
801 |
W1+119 |
bam
|
50.70
|
|
Metadata
|
|